Drugs of abuse testing by tandem mass spectrometry: a rapid, simple method to replace immunoassays.

Primary Objective: To replace immunoassay screening for drugs of abuse (DOA) with a cost-effective tandem mass spectrometry method.

Secondary Objective: To substantially expand the drugs of abuse assay menu.

Design And Methods: The requirement was to perform high throughput DOA screening for 200 urine specimens/day for 40 drugs/metabolites.