Publications by authors named "Nadine Ardo"
Article Synopsis
- Impaired lymphatic transport is linked to the development and worsening of atherosclerosis, with decreased LDLR expression playing a significant role rather than just high cholesterol levels.
- Research showed that enhancing lymphatic function in mice through a mutant form of VEGF-C delayed plaque formation when fed a high-fat diet, although the exact protective mechanisms of LDLR on lymphatic health remain unclear.
- The study indicates that reducing LDLR expression affects lymphatic contractility and leads to decreased protein levels of key lymphatic markers, suggesting that targeted treatments could help maintain lymphatic function and combat atherosclerosis progression.
