Efficacy and safety of single dose of oral secnidazole 2 g in treatment of bacterial vaginosis: A systematic review and meta-analysis.

Background: Bacterial vaginosis (BV) is a common disease characterized by vaginal discharge.

Objective: To evaluate the evidence from published randomized clinical trials (RCTs) about the efficacy and safety of single dose of oral secnidazole 2 g in comparison with other drugs.

Search Strategy: Electronic databases were searched using the following MeSH terms (bacterial vaginosis OR vaginosis) AND (secnidazole OR secnol OR sabima OR secnidal OR minovage).

Intralesional immunotherapy for the treatment of warts: A network meta-analysis.

Background: Without clear evidence, selecting among the existing immunotherapeutic options for warts remains challenging.

Objective: Through network meta-analyses, we aimed to evaluate the comparative efficacy of different intralesional immunotherapeutic modalities.

Methods: We included randomized controlled trials comparing intralesional immunotherapeutic modalities to cryotherapy, placebo, or imiquimod.