Publications by authors named "Nadia Tillouche"
Article Synopsis
- - Sirenomelia is a rare and severe birth defect with unknown causes, characterized by fused legs and serious internal organ issues.
- - Researchers studied nine families with this condition using advanced exome sequencing, identifying specific genetic variants in the CDX2 gene linked to two family cases, following an autosomal dominant inheritance pattern.
- - The study suggests a genetic role in sirenomelia, revealing additional potential gene variants and emphasizing the importance of the Cdx and Wnt signaling pathways in its development.
Background: Even in developed countries, severe specific pregnancy complications may occur in the immediate postpartum period and require admission to the ICU. The characteristics and risk factors of acute renal failure (ARF) induced by these complications and their treatments are not well known.
Methods: We performed a retrospective multicenter study in three intensive care departments linked to level III maternity wards in the north of France.
Article Synopsis
- This study investigated the impact of high-dose tranexamic acid (TA) on reducing blood loss in women experiencing postpartum hemorrhage (PPH) of over 800 mL after vaginal delivery.
- Conducted as a randomized, controlled trial with 144 participants, results showed that those receiving TA experienced significantly less blood loss and shorter bleeding duration compared to the control group.
- Despite mild side effects being more common in the TA group, the overall findings suggest that high-dose TA could effectively decrease blood loss and improve outcomes in managing PPH.
Objectives: To evaluate the contribution and limitations of fetal ultrasonography (US) and magnetic resonance imaging (MRI) for the diagnosis and management of migration disorders.
Methods: Over a 5-year period, 14 fetuses with pathological migration disorders, without an infectious context, were taken care of in our centre. All underwent US; nine underwent MRI as well.