Assessing air travel safety in neuromuscular disease: standard versus prolonged hypoxic challenge tests.

Purpose: The hypoxic challenge test (HCT) is used to evaluate safety for air travel in individuals with respiratory disease by breathing in 15% oxygen for 20 min. Our aim was to determine if a prolonged HCT, lasting 120 min, identified more individuals with neuromuscular disease at potential risk than the standard HCT lasting 20 min.

Methods: This was a cross-sectional study.

Association between fraction of exhaled nitrous oxide, bronchodilator response and inhaled corticosteroid type.

Background: Fraction of exhaled nitrous oxide (FeNO) is a known marker of airway inflammation and a topic of recent investigation for asthma control in children.

Objective: To investigate the relationship among FeNO and bronchodilator response measured by spirometry and types of inhaled corticosteroids (ICS).

Methods: A one-year review of children tested with spirometry and FeNO in a regional pediatric asthma centre was conducted.