Publications by authors named "Nadia Saad"

Herein, silver nanoparticles (Ag-NPs) were synthesized using an environmentally friendly approach by harnessing the metabolites of F2. The successful formation of Ag-NPs was checked by a color change to yellowish-brown, followed by UV-Vis spectroscopy, Fourier transforms infrared (FT-IR), Transmission electron microscopy (TEM), and X-ray diffraction (XRD). Data showed the successful formation of crystalline Ag-NPs with a spherical shape at the maximum surface plasmon resonance of 420 nm with a size range of 3-13 nm.

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In just two decades has attained considerable importance, evolving from an insignificant organism to a leading pathogen especially in intensive care unit settings globally. Treatment options are already very limited and have almost run out due to the rapid emergence of antimicrobial resistance. Evaluation of antimicrobials that are currently in use to determine their effectiveness against multidrug-resistant (MDR) strains and developing newer options is of utmost importance.

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Article Synopsis
  • The study aimed to distinguish Ambler class A, B, and D carbapenemase-producing Enterobacteriaceae using accessible lab methods, without special techniques.
  • Conducted at Army Medical College in Islamabad from November 2015 to November 2016, the research analyzed clinical specimens for resistance using methods like the disc diffusion and Modified Hodge tests.
  • Results showed that out of 45 samples, 95.45% produced carbapenemase, primarily KPC-type (88.3%), indicating a significant prevalence of KPC-producing Klebsiella pneumoniae in the healthcare setting.
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Objective: To determine the frequency and antibiogram of pathogens in an intensive care unit (ICU).

Study Design: Cross-sectional, observational study.

Place And Duration Of Study: Department of Microbiology, Army Medical College, National University of Science and Technology, Islamabad, from January 2013 to January 2014.

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Objective: To evaluate sensitivity and specificity of disc approximation test compared to three-dimensional extract test as a phenotypic gold standard test for detection of AmpC beta-lactamase producing Escherichia coli and Klebsiella pneumoniae.

Methods: The cross-sectional validation study was conducted from November 2014 to April 2015 at Army Medical College, Rawalpindi, Pakistan. Extended spectrum beta lactamases (ESBLs) were isolated from various clinical specimens.

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Objective: To assess the in vitro efficacy of doripenem against Pseudomonas aeruginosa and Acinetobacter baumannii using Epsilometer strips.

Study Design: Cross-sectional study.

Place And Duration Of Study: Department of Microbiology, Army Medical College, Rawalpindi and National University of Sciences and Technology, Islamabad, from May 2014 to September 2014.

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Objective: To compare the in vitro antimicrobial efficacy of ceftaroline with linezolid against Staphylococcus aureus and methicillin resistant Staphylococcus aureus.

Study Design: Quasi-experimental study.

Place And Duration Of Study: Microbiology Department, Army Medical College, Rawalpindi, from January to December 2013.

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