Purpose: To investigate the effect of statins on the risk for age-related macular degeneration (AMD) treated with photodynamic therapy (PDT).
Methods: All members in one district of a health maintenance organization in Israel, older than 50 years (n = 139,894), were included. PDT procedures for AMD (775 procedures; 283 patients) and filled statin prescriptions between 1999 and 2002 (471,232 prescriptions; 29,417 patients) were documented.
Objective: To identify USH2A mutations in Israeli patients with autosomal-recessive Usher syndrome type 2 (USH2) and retinitis pigmentosa (RP).
Methods: Patients from 95 families with RP and 4 with USH2 were clinically evaluated. USH2A exons 2-72 were scanned for mutations using single-strand conformation and sequencing analyses.
Purpose: To investigate the association between cataract surgery and the rate of photodynamic therapy (PDT) for age-related macular degeneration (AMD).
Design: Observational population-based retrospective case-control study.
Participants: All members in a district of the largest health maintenance organization (HMO) in Israel > 50 years old on January 1, 2001, who did not terminate their membership through May 31, 2005 (139 894 members).
Purpose: To evaluate the risk of ocular surface herpetic eye disease (osHED) in allergic eye disease.
Methods: We calculated the risk for osHED in 11,205 patients on antiallergic ocular topical agents compared with 453,069 controls based on filled prescriptions for topical acyclovir between 2001 and 2003.
Results: Significantly more allergic patients, of all age groups, received treatment for osHED (p < 0.
Purpose: To investigate the influence of various risk factors for age-related macular degeneration (AMD) on the rate of undergoing photodynamic therapy (PDT).
Design: An observational population based cohort study.
Settings: A district of the largest health maintenance organization (HMO) in Israel.
Purpose: To investigate the effect of topical beta-blockers on the prevalence of depression among glaucoma patients.
Design: Retrospective observational population-based cohort study.
Participants: We reviewed the electronic medical records of all the members in a district of the largest health maintenance organization in Israel (Central District of Clalit Health Services) who were older than 20 years (317,469 members).
Purpose: To study the incidence of herpetic eye disease (HED) of the ocular surface in diabetics.
Design: Observational historical cohort study.
Setting: A district of the largest health maintenance organization in Israel (the Central District of Clalit Health Services).
Ocul Immunol Inflamm
September 2005
Purpose: To report a case of severe blepharoconjunctivitis induced by a peeling mask.
Methods: A 32-year-old healthy female was examined one day after undergoing a face-peeling procedure with a mask containing trichloroacetic acid. She complained of severe burning, redness, and epiphora in her left eye that started several hours after the procedure.
Purpose: To evaluate the ultrasonographic tissue characteristics of mushroom-shaped versus dome-shaped uveal melanoma and to compare them with the tumor vasculature.
Methods: We examined clinically and ultrasonically 18 dome-shaped and 11 mushroom-shaped uveal melanomas (29 consecutive patients; mean age 57 years) and compared their normalized A-scan patterns. Using histological sections from a different set of patients (12 dome- and 17 mushroom-shaped tumors), we calculated the percentage of area covered by blood vessels.
Purpose: To compare the prevalence of keratoconjunctivitis sicca (KCS) in a prospective cohort of 22,382 diabetic patients with that in the general population.
Design: Prospective, observational, cohort study.
Setting: A district of israel's largest health maintenance organization.
Purpose: To describe prescription trends within a managed care setting for glaucoma medications and to examine the effect of introduction of Cosopt--a fixed combination of dorzolamide and timolol.
Patients And Methods: All prescriptions dispensed to any of the 470,350 members of an Israeli health maintenance organization were monthly scanned for patients treated for glaucoma, between January 2000 and May 2003. The monthly mean number of glaucoma patients was 3899 +/- 104 (mean +/- SD).