The endocrine milieu in naturally matured follicles is different in women with high serum anti-Müllerian hormone concentrations.

Research Question: Is the endocrine milieu different in women with low serum anti-Müllerian hormone (AMH) concentration compared with women with high concentration?

Design: Cohort study of 84 women (four groups) classified according to AMH concentration and age undergoing natural cycle IVF treatment. Concentrations of LH, oestradiol, testosterone, androstenedione and AMH were determined in follicular fluid (FF), associations analysed and clinical outcome parameters evaluated.

Results: A positive correlation between serum and FF AMH concentrations was confirmed.