Publications by authors named "Nadia F Elameen"
Article Synopsis
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects various body systems, leading to a low quality of life for patients despite better survival rates over the years.
- * This study aimed to examine the changes in quality of life for SLE patients using the Lupus QoL scale and how it relates to pulmonary complications and other disease factors.
- * Results indicated that quality of life correlates strongly with lung function and negatively with symptoms of dyspnea and damage observed in lung scans, highlighting the impact of respiratory issues on overall well-being.
Background: Although the significance of inflammatory cytokines and chemokines in the pathogenesis of SLE is well established, the findings showed diversity and implied that combining different biomarkers could be useful in monitoring disease activity or organ involvement. Despite the potentially high prevalence of lung involvement in SLE, only a few studies have investigated for lung biomarkers.
Objective: The aim of this study was to assess the value of Chemokine Ligand 21 (CCL 21) and Interferon gamma-induced protein 10 (IP10) as serum biomarkers for pulmonary involvement in SLE and their correlation with disease activity, organ involvement, pulmonary function tests (PFTs), and chest CT findings.