Psoriasis in obesity: comparison of serum levels of leptin and adiponectin in obese subjects - cases and controls.

Background: Psoriasis and obesity are somewhat related to a low-grade systemic inflammatory response.

Objectives: To determine leptin and adiponectin levels in psoriasis patients compared to control patients matched for weight.

Methods: A case-control study was performed, evaluating 113 psoriasis patients and 41 controls with other dermatologic diseases.

Assessment of adiposity in psoriatic patients by dual energy X-ray absorptiometry compared to conventional methods.

Background: Obesity is considered a chronic low-grade inflammatory disease that shares mediators of inflammation with psoriasis, such as TNF-α and IL-6. The relationship between these two conditions involves factors such as predisposition and response to therapy, in addition to an association with cardiovascular disease.

Objectives: The aim of the present study was to investigate the prevalence of adiposity as determined by body mass index (BMI), waist circumference (WC), and dual energy X-ray absorptiometry (DXA) evaluation in patients with psoriasis.

Psoriasis: new comorbidities.

Psoriasis is a chronic inflammatory disease associated with several comorbidities. A few decades ago, it was considered an exclusive skin disease but today it is considered a multisystem disease. It is believed that 73% of psoriasis patients have at least one comorbidity.