New Ocular Associations in Sanjad-Sakati Syndrome: Case report from Oman.

Sanjad-Sakati syndrome (SSS; Online Mendelian Inheritance in Man [OMIM] #241410), also known as hypoparathyroidism-retardation-dysmorphism (HRD) syndrome, is an autosomal recessive disorder in which prenatal-onset extreme growth retardation, congenital hypoparathyroidism and craniofacial dysmorphism result from mutations in the tubulin-specific chaperone E (TBCE) gene on chromosome 1q42-43. We report unique ophthalmic findings in a two-year-old child with molecularly confirmed SSS, who was admitted to Sultan Qaboos University Hospital in Oman at 11 weeks old with bilateral congenital corneal clouding. The ophthalmic findings in this patient were linked to faulty microtubule assembly in the brain, abnormal intracellular membrane transport and the resulting metabolic derangement seen in patients with SSS.

Confoscan: an ideal therapeutic aid and screening tool in acanthamoeba keratitis.

Although present worldwide, Acanthamoeba keratitis (AK) is a rare condition. It is a protozoal infection of the eye that is generally caused by wearing contaminated contact lenses or lens solutions. Confoscan and confocal scanning laser tomography (CSLT) are in vivo noninvasive diagnostic tools which provide high definition images of corneal microstructures.

Subjective and quantitative measurement of wavefront aberrations in nuclear cataracts - a retrospective case controlled study.

Purpose: To measure, quantify and compare Ocular Aberrations due to nuclear cataracts.

Setting: Department of ophthalmology and school for ophthalmic technicians, college of medicine and health sciences, Sultan Qaboos University, Muscat, Oman.

Design: Retrospective case controlled study.

Culture Negative Confoscan Positive Acanthamoeba Keratitis: A relentless course.

Acanthamoeba keratitis is a protozoal infection of the eye, mainly due to the use of non-sterile solutions, like saline for disinfecting contact lenses. We report a case where delay in the diagnosis of acanthamoeba keratitis due to inadequate laboratory investigations and clinical management led to an excruciatingly painful course of the disease. The importance of non-invasive imaging techniques of confocal microscopy in the diagnosis of acanthamoeba keratitis, in the absence of positive culture reports, is highlighted in this case.

Bevacizumab therapy for macular edema in central retinal vein occlusion: Long-term results.

Background: There is no proven effective treatment for vision loss in central retinal vein occlusion (CRVO). Bevacizumab has been reported in small series with limited follow-up, to have a positive effect in reducing cystoid macular edema (CME) and improving vision in CRVO.

Purpose: To report long-term results with the use of bevacizumab in CRVO.

Photodynamic therapy with verteporfin for chronic central serous choroidoretinopathy and idiopathic choroidal neovascularization-first report from the sultanate of oman.

Background: Central Serous Chorioretinopathy (CSCR) is characterized by accumulation of subretinal fluid, resulting in neurosensory retinal detachment.

Design: Interventional study.

Methods: Five patients (CSCR-3; Idiopathic-2) with Choroidal Neovascularization (CNV) were selected for the study.