Publications by authors named "Nadezhda A Pechnikova"
Magnetogenetics emerges as a transformative approach for modulating cellular signaling pathways through the strategic application of magnetic fields and nanoparticles. This technique leverages the unique properties of magnetic nanoparticles (MNPs) to induce mechanical or thermal stimuli within cells, facilitating the activation of mechano- and thermosensitive proteins without the need for traditional ligand-receptor interactions. Unlike traditional modalities that often require invasive interventions and lack precision in targeting specific cellular functions, magnetogenetics offers a non-invasive alternative with the capacity for deep tissue penetration and the potential for targeting a broad spectrum of cellular processes.
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- Fetal lung development is a critical process that affects respiratory health after birth, and disruptions can lead to disorders that impact both neonatal and adult health.
- Recent studies highlight a link between fetal lung disorders and the development of diseases in adulthood, offering insights into why certain health issues arise later in life.
- The article explores various stages of fetal lung development, specific disorders like respiratory distress syndrome and congenital diaphragmatic hernia, and the possible mechanisms behind these associations, emphasizing the need for targeted preventive measures and ongoing research.
Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their contrast properties and inducing toxicity. Here, we describe observation of the full lifecycle of 40-nm magnetic particles from their injection to the complete degradation in vivo and associated impact on the organism.
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