Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia.

Background: Colorectal cancer (CRC) is the third most common cancer worldwide with approximately 1 million cases diagnosed annually. In Malaysia, CRC is the second most common cancer in women and ranked first in men. The underlying cause of CRC remains unknown.

Treatment of delayed chylothorax complicating oesophagectomy.

A patient with carcinoma of the cardia underwent Ivor-Lewis oesophagogastrectomy. He developed right chylothorax postoperatively, which is a rare complication. Attempts to treat the chylothorax by conservative means and thoracoscopic ligation failed.

Inguinal hernia repair by surgical trainees at a Malaysian teaching hospital.

Objective: To assess the outcome of inguinal hernia repaired by surgical trainees at Universiti Kebangsaan Malaysia Hospital.

Methods: Retrospective review of 103 patients who underwent surgery between November 2001 and October 2002.

Results: The mean age of patients was 50 years and the male-to-female ratio was 20:1.