Photon antibunching control in a quantum dot and metallic nanoparticle hybrid system with non-Markovian dynamics.

Photon-number statistics of the emitted photons from a quantum dot placed in the vicinity of a metallic nanoparticle driven by a laser in the non-Markovian regime is investigated theoretically. In the model scheme, the quantum dot is considered as an InAs three-level system in L-type configuration with two transition channels. We aim to introduce the hybrid system as a nonclassical photon source and control the antibunching behavior of the emitted photons by the geometrical as well as the physical parameters of the hybrid system.

Determining the effect of implementing an educational package on quality of life among patients with chronic obstructive pulmonary disease referring to teaching hospitals affiliated with Ilam University of Medical Sciences in 2016.

Introduction: Nowadays, pulmonary diseases have become one of the most important causes of mortality in the world. In this regard, the present study was aimed at examining the effect of implementing an educational package on quality of life (QoL) among patients with chronic obstructive pulmonary disease (COPD) referring to teaching hospitals affiliated with Ilam University of Medical Sciences.

Materials And Methods: The present study was an interventional clinical trial in which the participants were randomly assigned into an intervention group and a control group.

Studying the factors related to refractive error regression after PRK surgery.

Backgtound: Photorefractive keratectomy (PRK) is used for a wide range of refractive errors such as low to moderate myopia, hyperopia and astigmatism. While many improvements have been made in laser application and accuracy as well as the modes of corneal flap removal, and although the results are somewhat predictable, regression of refractive errors is still a common complaint among the patients undergoing refractive surgery with Excimer Laser. We aimed to determine related factors of regression following photorefractive keratectomy (PRK) in different types of refractive errors.

Anthropometric Indices from Primary to High School in the West of Iran: Epidemiologic Trends.

Examining the trend of anthropometric indices in children and adolescents in each region can be highly beneficial in providing effective strategies to improve the status of their growth. This study was conducted with the aim of determining the trend of anthropometric indices in students from primary to high school in the west of Iran. Data were collected using a demographic questionnaire and health certificates for anthropometric information of primary school students, and current anthropometric measurements with scale for high school students.

eModel-BDB: a database of comparative structure models of drug-target interactions from the Binding Database.

Background: The structural information on proteins in their ligand-bound conformational state is invaluable for protein function studies and rational drug design. Compared to the number of available sequences, not only is the repertoire of the experimentally determined structures of holo-proteins limited, these structures do not always include pharmacologically relevant compounds at their binding sites. In addition, binding affinity databases provide vast quantities of information on interactions between drug-like molecules and their targets, however, often lacking structural data.

A Study of Corneal Biomechanics in Delayed-Onset Mustard Gas Keratopathy Compared to Cases With Corneal Scarring and Normal Corneas.

Purpose: This study compares the corneal biomechanical properties, as measured with Corvis ST, in three groups of cases with delayed-onset mustard gas keratopathy (DMGK), chronic corneal scarring (CCS), and those with normal corneas.

Methods: Forty-five eyes were enrolled in the DMGK, CCS, and normal groups (15 eyes each). All patients were examined with the slitlamp and Corvis ST.

Treatment of striae distensae using fractional ablative CO laser in skin types II-IV: a retrospective case series study.

Striae distensae (SD) are atrophic dermal scars often found on abdomen, breasts, thighs, and hips of pregnant women. The strias' self-healing without any intervention is a poor possibility. Till now, several lasers and light sources have been used for treatment of SD.

Study of the Relationship between HPA-1 and HPA-5 Gene Polymorphisms and Refractory to Platelet Therapy and Recombinant Factor VII in Glanzmann Thrombasthenia Patients in Southeast of Iran.

Glanzmann Thrombasthenia (GT) is a rare autosomal disease. HPA (Human Platelet Alloantigen) is a surface polymorphic alloantigen of platelets. This study was intended to investigate and compare the polymorphism of HPA-1 and HPA-5 genes in two groups of GT patients, with and without resistance to platelet and recombinant factor VII therapy.

Leukocyte Telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia.

Background: Telomeres are involved in chromosomal stability, cellular immortality and tumorigenesis. Human telomerase reverse transcriptase (TERT) is essential for the maintenance of telomere DNA length. Recently, a variable tandem-repeats polymorphism, MNS16A, located in the downstream region of the TERT gene, was reported to have an effect on TERT expression and telomerase activity.

Evolutionary applications of phylogenetically-informed ecological niche modelling (ENM) to explore cryptic diversification over cryptic refugia.

We used the fat dormouse (Glis glis), a species from a monotypic genus of family Gliridae, as a model to promote the understanding of patterns of cryptic diversification along the ancient Hyrcanian Forests, one of the old-growth relicts of the temperate deciduous forests worldwide. Mitochondrial Cytb data was used to investigate the phylogenetic status of two geographically-different populations of G. glis along the Hyrcanian Forests among all the worldwide known lineages of the species.

Effectiveness of vitamin D therapy in improving metabolomic biomarkers in obesity phenotypes: Two randomized clinical trials.

Background: Uncertainty remains about the effect of vitamin D therapy on biomarkers of health status in obesity. The molecular basis underlying this controversy is largely unknown.

Objective: To address the existing gap, our study sought to compare changes in metabolomic profiles of obesity phenotypes (metabolically healthy obese (MHO) and metabolically unhealthy obese (MUHO)) patients with sub-optimal levels of vitamin D following vitamin D supplementation.

Aerobic training improves platelet function in type 2 diabetic patients: role of microRNA-130a and GPIIb.

Aims: MicroRNAs (miRs) that are mediators of gene expression have been implicated in type 2 diabetes mellitus (T2DM). Platelet hyper-reactivity is one of the most important disorders in T2DM patients. In this study, we explored the effects of aerobic training (AT) on platelet aggregation and Glycoprotein IIb (GPIIb) receptor and miR-130a expression.

Antigenic targets of CAR T Cell Therapy. A retrospective view on clinical trials.

Chimeric antigen receptor (CAR) T cell therapy is anticipated to be increasingly implemented in the context of cancer treatment after two current FDA approval of anti-CD19 CAR-T cells (Kymriah™ & Yescarta™). The success of CD19 is mainly attributable to the proper selection of the antigen, CD19, as the target of the disease, highlighting the importance of target selection for other CAR therapies. Therefore, here we performed a global analysis of targets that are the prime focus for various CAR T cell therapies in human clinical trials.

Persian leopard's (Panthera pardus saxicolor) unnatural mortality factors analysis in Iran.

Due to the relatively low offspring survival rate, surviving adult leopards play a critical role in the species' viability. The unnatural mortality of leopards, caused by human activities can seriously compromise the species' long-term population survival. An analysis of spatial distribution and sex ratio of unnatural mortality of 147 recorded Persian leopard (Panthera pardus saxicolor) carcasses during a fifteen-year period (from 2000-2015) in Iran indicated that road mortality is the second most frequent cause of unnatural mortality of Persian leopards' after illegal hunting (or prey poisoning, such as poisoned meat) by villagers, shepherds and military forces.

Future heat stress arising from climate change on Iran's population health.

Climate change-induced extreme heat events are becoming a major issue in different parts of the world, especially in developing countries. The assessment of regional and temporal past and future change in heat waves is a crucial task for public health strategies and managements. The historical and future heat index (HI) time series are investigated for temporal change across Iran to study the impact of global warming on public health.

Large-scale computational drug repositioning to find treatments for rare diseases.

Rare, or orphan, diseases are conditions afflicting a small subset of people in a population. Although these disorders collectively pose significant health care problems, drug companies require government incentives to develop drugs for rare diseases due to extremely limited individual markets. Computer-aided drug repositioning, i.

Effects of endurance training on hsa-miR-223, P2RY12 receptor expression and platelet function in type 2 diabetic patients.

Background: Type 2 diabetes mellitus (T2DM) is associated with thrombotic events due to platelets' defects.

Objective: The aim of this study was to investigate the effects of endurance training on expressions of platelet hsa-miR-223 and P2RY12 receptor, as well as platelet function in T2DM patients.

Methods: Twenty female T2DM patients (age, 62.