Neuroprotective potential of Beta vulgaris L. in Parkinson's disease.

Objective: The objective was to investigate the neuroprotective role of Beta vulgaris in Parkinson's disease (PD).

Materials And Methods: PD was induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.

Cognitive enhancing effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on learning and memory.

Objective: The present study was designed to investigate cognitive enhancing property of angiotensin-converting enzymes inhibitors (ACEI) and angiotensin receptor blockers (ARBs) in rats.

Materials And Methods: The elevated plus maze (EPM), passive avoidance test (PAT), and water maze test (WMT) were used to assess cognitive enhancing activity in young and aged rats. Ramipril (10 mg/kg, p.

Protective effect of sitagliptin and rosuvastatin combination on vascular endothelial dysfunction in type-2 diabetes.

The present investigation aimed to evaluate the protective effects of sitagliptin, glimepiride, rosuvastatin and their combinations on oxidative stress and endothelial dysfunction in the aortic tissues in fructose-fed type-2 diabetic rats. Sitagliptin (20 mg/kg, p.o.

Protective effect of nebivolol on reserpine-induced neurobehavioral and biochemical alterations in rats.

Reserpine-induced orofacial dyskinesia is a model that shares some mechanists' aspects with tardive dyskinesia whose pathophysiology has been related to oxidative stress. The present study was aimed to explore neuroprotective effects of nebivolol, an antihypertensive agent, on reserpine-induced neurobehavioral and biochemical alterations in rats. Reserpine (1mg/kg, s.

Effect of bromocriptine on cardiovascular complications associated with metabolic syndrome in fructose fed rats.

Objective: The objective of the present study was to evaluate the effect of bromocriptine on cardiovascular complications associated with type-2 diabetes mellitus (DM).

Materials And Methods: Metabolic syndrome or type 2 DM was induced by administration of fructose (66% solution, p.o.

Cognitive enhancing and antioxidant activity of ethyl acetate soluble fraction of the methanol extract of Hibiscus rosa sinensis in scopolamine-induced amnesia.

Objective: The objective of the present study was to evaluate the cognitive enhancing and antioxidant activity of Hibiscus rosa sinensis.

Materials And Methods: The learning and memory was impaired by administration of scopolamine (1 mg/kg, i.p.

Anti-stress effect of ethyl acetate soluble fraction of Morus alba in chronic restraint stress.

Context: Restraint stress is a well-known method to induce chronic stress which leads to alterations in various behavioral and biochemical parameters.

Objective: The present work was designed to study anti-stress effects of Morus alba in chronic restraint stress (RS)-induced perturbations in behavioral, biochemical and brain oxidative stress status.

Materials And Methods: The stress was produced by restraining the animals inside an adjustable cylindrical plastic tube for 3 h once daily for ten consecutive days.

Neuroprotective effect of Hibiscus rosa sinensis in an oxidative stress model of cerebral post-ischemic reperfusion injury in rats.

Context: The ischemic brain lesions induced in rats by temporary occlusion of the bilateral common carotid arteries and restoration of blood flow to an ischemic brain region is associated with generation of reactive oxygen species with consequent reperfusion injury.

Objective: The present study investigated the neuroprotective potential of Hibiscus rosa sinensis L. (Malvaceae) in a bilateral common carotid artery (BCCA) occlusion model of global cerebral ischemic reperfusion.

Protective effect of Morus alba leaves on haloperidol-induced orofacial dyskinesia and oxidative stress.

Long-term treatment with haloperidol, a typical neuroleptic, induces neurodegeneration caused by excitotoxicity and oxidative stress, which play an important role in the development of orofacial dyskinesia. In the present investigation, an attempt has been made to examine the effect of a concomitant treatment of methanol extract of Morus alba Linn. (Moraceae) leaves (100-300 mg/kg, i.

Adaptogenic effect of Morus alba on chronic footshock-induced stress in rats.

Objective: The objective of the present study was to evaluate the adaptogenic property of the ethyl acetate-soluble fraction of methanol extract of Morus alba roots against a rat model of chronic stress (CS).

Materials And Methods: Rats were exposed to stress procedure for 21 days. The stress procedure was mild, unpredictable footshock, administered for 1 h once daily for 21 days.

Effect of Hibiscus rosa sinensis on reserpine-induced neurobehavioral and biochemical alterations in rats.

Effect of methanolic extract of Hibiscus rosa sinensis (100-300 mg/kg) was studied on reserpine-induced orofacial dyskinesia and neurochemical alterations. The rats were treated with intraperitoneal reserpine (1 mg/kg, ip) for 3 days every other day. On day 5, vacuous chewing movements and tongue protrusions were counted for 5 min.

Anti-dopaminergic effect of the methanolic extract of Morus alba L. leaves.

Objective: To evaluate the effect of methanolic extract of Morus alba L. leaves on dopaminergic function.

Materials And Methods: The effect of the methanolic extract of Morus alba L.

Effect of Morus alba L. (mulberry) leaves on anxiety in mice.

Objective: The aim of the present work is to evaluate the anxiolytic effect of a methanolic extract of Morus alba L. leaves in mice.

Materials And Methods: The hole-board test, elevated plus-maze paradigm, open field test, and light/dark paradigm were used to assess the anxiolytic activity of the methanolic extract of M.