The Effect of Strontium Ranelate Gel on Bone Formation in Calvarial Critical Size Defects.

Aim: The current study was designed to investigate the effectiveness of locally applied Strontium ranelate to induce bone formation.

Materials And Methods: Forty-eight female rats were divided into six groups (eight rats in each group): The three test groups included Strontium (SR) 2.5 mg, 5 mg and 10 mg that was dissolved in methylcellulose gel.