Publications by authors named "Nada Konstantinidis"
Background: Killer cell immunoglobulin-like receptors (KIRs) are glycoproteins regulating the response of natural killer (NK) cells and a few sub-sets of T-cells. The KIR gene frequencies and genotype content vary considerably among different ethnic groups.
Aim: The aim of this study was to analyse KIR gene polymorphism in the population of Vojvodina and to compare it with selected worldwide populations.
Introduction: A family of a child with cancer needs continuous help and support from medical and other professionals, relatives, friends and community at the moment of making diagnosis and during the treatment. The goal of this study was to find out the most frequent sources of individual or community based psychological support, reported by parents of children suffering from malignant diseases. We focused on the help received at the moment of making diagnosis and within the first and second year of treatment.
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- Biphenotypic acute leukaemia features blasts that express both myeloid and either B- or T-lymphoid antigens, making it a rare and complex condition.
- Two pediatric cases illustrate the challenges in treating this leukaemia type: one patient had Philadelphia chromosome positivity and underwent intensive therapy but ultimately died from complications, while the other did not achieve remission despite treatment.
- The diagnosis relies heavily on immunophenotyping, and treatment must be tailored based on the individual patient's immunophenotype and genetic profile, emphasizing the need for more intensive and personalized approaches.
Introduction: Phenylketonuria is a genetic disorder of metabolism of amino acid phenylalanine, which results in the absence of phenylalanine hydroxylase, an enzyme that catalyzes the conversion of phenylalanine into tyrosine. It is an autosomal recessive disorder. Screening for phenylketonuria in Voivodina started in 2003.
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