Brucellosis in children in Bosnia and Herzegovina in the period 2000 - 2013.

Aim: To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.

Methods: The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis of brucellosis was established based on anamnestic data, clinical features and positive results from blood culture and/or positive results from one of the serological tests.

Results: In this period, a total of 2630 patients, 246 (9.

Staphylococcal bacteraemia/sepsis-characteristics of laboratory parameters.

Introduction: While determining a diagnosis and during a disease follow-up, laboratory, or non-specific inflammatory parameters in particular, platelets reference values, nitrogen matters, and liver enzymes play a significant role because their values may indicate multiple organ failures.

Goals: To analyse laboratory parameters in patients diagnosed with the staphylococcal bacteraemia/sepsis.

Patients And Methods: Analysed patients have been treated at the Clinic for Infectious Diseases through the period often years.

Frequency of in-hospital acquired staphylococcus bacteremia/sepsis within ten-year period.

Unlabelled: Analyzing data in the literature, it is noted that in-hospital acquired infections are an increasing problem even in more developed countries. This increasing trend is related to the progress of medical science and introduction of new invasive diagnostic-therapeutic methods, as well as increase of multiresistant types of bacteria, including staphylococci in big percentages.

Goals: To analyze frequency of in-hospital acquired staphylococcus bacteremia/sepsis.

Clinical and epidemiological characteristics of novel AHIN1 flu.

Introduction: Swine influenza is respiratory infection caused by virus influenza A H1N1.

Objective: To show epidemiological and clinical characteristic of patients with confirmed influenza A H1N1 hospitalized at Clinic for Infectious Diseases of University Clinical Center Sarajevo.

Material And Methods: We analyzed 127 medical records of patients with microbiologically confirmed pandemic influenza A/H1N1 (nasopharyngeal swab analyzed by PCR method).

Listeria meningoencephalitis in an immunocompetent person.

Listeria monocytogenes is a small, aerobic or facultative anaerobic, non-sporulating gram positive bacillus that can be isolated from soil, vegetation or animal reservoirs. There are six species of Listeria, and only L. monocytogenes is pathogenic for humans.

[Evaluation of hepatitis C virus genotype and its influence on therapeutical respond on combined therapy with pegilated interferon A 2a (40)kD and ribavirin].

The aim of our study was to determine the genotypes of viral hepatitis C. We examined 54 patients with chronic hepatitis C who were treated at Gastroenterohepatology Department University of Sarajevo. We also monitored effects of therapeutical results in same group of patients.

[Hospital sepsis and aggressive medical interventions].

Aim: To find out do the aggressive medical interventions have an effect on appearance of gram positive and gram negative hospital sepsis among 200 patients with positive clinical and laboratorial signs of sepsis and who have proved monomicrobial blood isolates.

Methods: Samples of septic patients were analyzed statistically by using x2 test and coefficient of contingency C.

Results: After we put gram negative so as gram positive sepsis to a correlation with the aggressive medical treatments, which proceeded, we got statistically significant results.

[Meningoencephalitis tuberculosis--primary isolation of resistant M. tuberculosis].

Tuberculosis is one of the main causes of serious diseases in developing countries. Despite of decreasing tuberculosis in industrial countries, diseases is not eradicated. In last fifth years the picture of diseases is changed with large number atypical cases.

[Sepsis--clinical parameters of recognition and differentiation].

Introduction: Even today, early recognition of sepsis remains a great problem, requiring the search for clinical symptoms and signs with predictive features.

Aim: to define the number of days of disease till hospitalization and value of some clinical signs in recognition and differentiation of patients with monomicrobial (M.A) gram positive and gram negative sepsis.

[Hospital sepsis and pre-existing disease].

Aim: By retrospective study in a fifteen period from 1990 to 2004 to research if a pre-existential disease influences the appearance of gram-positive and gram-negative clear determinated hospital sepsis among 200 septic patients, selected by a random method and with clinic-laboratory signs of sepsis and monomicrobial blood culture.

Methodology: Specimen of septic patients analysed in relation to the patient condition and statistically processed using chi2 test and contigential coefficient C.

Results: We received statistically significant results when we have correlated gram-negative hospital sepsis and pre-existential disease, until this significancy was absent in gram-positive hospital sepsis.

[Analysis of amoxicillin-clavulanic acid (Xiclav) efficacy and the possibility of early switch from parenteral to oral therapy in the treatment of infections].

Early transition from parenteral to oral antibiotic therapy switch therapy play a major role in treatment because of adverse reactions of long parenteral therapy. In the prospective, comparative and randomized clinical study the efficacy of two treatment regimens were analyzed: XICLAV (amoxicillin + clavulanic acid): parenteral regiment with early transition to oral therapy and parenteral regimen in patients with bacterial infections without transition to the oral dosage form, on the other hand. In our study we've analyzed 240 hospitalized patients in the Clinic of infectious Diseases in Tuzla and Sarajevo too, so in the Institution for infectious diseases in Zenica.