Cytokines profiles in Sudanese women with preeclampsia.

Background: Cytokine imbalance in preeclampsia may be one of the etiological factors for preeclampsia.

Objectives: The study was conducted to investigate interferon gamma (IFN-gamma), interleukin-4 (IL-4) and interleukin-10 (IL-10) in preeclampsia. Enzyme-linked immunosorbent assay (ELISA) was used to measure the concentrations of these three pro-inflammatory cytokines in sera from 33 Sudanese women with preeclampsia (at presentation and 7 days later) and 32 women with normal pregnancy as a control group.

Peripheral, placental and cord cytokines profile in spontaneous labor and elective caesarean section.

Background: Cesarean section delivery can lead to much maternal morbidity. Different cytokines have been reported to be influenced by the mode of delivery.

Objective: To investigate the influence of mode of delivery on maternal, placental and cord sera of interferon gamma (IFN-gamma), interleukin-4 (IL-4) and interleukin-10 (IL-10) levels.

Cytokine profiles in peripheral, placental and cord blood in an area of unstable malaria transmission in eastern Sudan.

Background: Understanding the cytokine interactions that underlie both control and disease should be helpful when investigating the pathogenesis of malaria during pregnancy. Few data exists concerning pathogenesis of malaria during pregnancy in areas of unstable malaria transmission.

Objectives: The study was conducted in New Halfa hospital, eastern Sudan, which is characterized by unstable malaria transmission to investigate the cytokine profiles in peripheral, placental and cord blood in parturient women.