Rare variant burden analysis from exomes of three consanguineous families reveals and as potential key proteins in inflammatory bowel disease pathogenesis.

Background: Inflammatory bowel disease (IBD) is a chronic autoimmune disorder characterized by severe inflammation and mucosal destruction of the intestine. The specific, complex molecular processes underlying IBD pathogenesis are not well understood. Therefore, this study is aimed at identifying and uncovering the role of key genetic factors in IBD.

Single nucleotide polymorphisms in the growth hormone receptor gene and polymorphisms in the diacylglycerol acyltransferase 1 gene as related to meat production in sheep.

Aim: This study aimed to investigate the polymorphisms in genes related to meat production, including growth hormone receptor () and diacylglycerol acyltransferase 1 () genes, in different breeds of sheep, including Barki, Najdi, and Harri.

Materials And Methods: Blood samples were collected from 75 randomly selected healthy Barki, Najdi, and Harri breeds of sheep, with 25 samples per breed. and genes were identified using a single nucleotide polymorphism assay followed by digestion with the restriction enzyme .

Molecular and cytogenetic assessment of Dipterygium glaucum genotoxicity.

The aim of the present study is to assess the genotoxicity of Dipterygium glaucum grows widely in Saudi Arabia desert to produce safety herbal products. This work is considered the first and pioneer report so far due to the lack and poor evaluated reports of the plant species for their mutagensity, genotoxicity and cytogenetics effects. Cytogenetic effects of D.