Neutrophil-like Cell-Membrane-Coated Nanozyme Therapy for Ischemic Brain Damage and Long-Term Neurological Functional Recovery.

Oxidative stress and a series of excessive inflammatory responses are major obstacles for neurological functional recovery after ischemic stroke. Effective noninvasive anti-inflammatory therapies are urgently needed. However, unsatisfactory therapeutic efficacy of current drugs and inadequate drug delivery to the damaged brain are major problems.

Efficient Electrochemical Sensor Based on Gold Nanoclusters/Carbon Ionic Liquid Crystal for Sensitive Determination of Neurotransmitters and Anti-Parkinson Drugs.

Herein we introduce a simple and sensitive sensor for the electrochemical determination of neurotransmitters compounds and anti-Parkinson drugs. The electrochemical sensor (Au/CILCE) based on gold nanoclusters modified carbon ionic liquid crystal (ILC) electrode was characterized using scanning electron microscopy and voltammetry measurements. The effect of ionic liquid type in the carbon paste composite for the electro-catalytic oxidation of L-dopa was evaluated.

Cobalt Oxide Nanoparticles/Graphene/Ionic Liquid Crystal Modified Carbon Paste Electrochemical Sensor for Ultra-sensitive Determination of a Narcotic Drug.

Drug-abuse, namely morphine (MO) affects the metabolism of neurotransmitters such as dopamine (DA). Therefore, it is crucial to devise a sensitive sensing technique to simultaneously determine both compounds in real samples. The fabrication of the sensor is based on in situ modification of a carbon paste (CP) electrode with cobalt oxide nanoparticles, graphene, and ionic liquid crystal in presence of sodium dodecyl sulfate; CoGILCCP-SDS.