Publications by authors named "Nada Elsheikh"

Article Synopsis
  • - The study investigates the Intra-Discal Vacuum Phenomenon (IDVP) in lumbar spines of people over 60, finding that IDVP is common, affecting over 50% of the sample, and its severity increases towards the lower spine.
  • - Using CT scans, researchers analyzed 2020 cases to understand how age, pelvic incidence (PI), and degenerative issues like fractures impact the occurrence of IDVP.
  • - Results suggest that lower pelvic incidence correlates with higher IDVP rates, especially at the L5S1 level, and reveal connections between IDVP and other spinal degenerative conditions, contributing to the understanding of aging spine mechanics.
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Article Synopsis
  • The study involved analyzing CT scans of the lumbar spine in older adults to understand the relationship between intradiscal vacuum phenomenon (IDVP) and disc degeneration over time.
  • Results showed that while most cases of IDVP stayed at a similar severity, some worsened, improved, or fused, with new cases developing in some patients during the study period.
  • Interestingly, the presence of IDVP did not correlate with significantly worse back pain among participants, suggesting that back pain experiences vary despite degeneration severity.
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The oncogenic effects of long non-coding RNA (lncRNA) Nicotinamide Nucleotide Transhydrogenase-antisense RNA1 (NNT-AS1) role in colorectal cancer (CRC) hasn't been sufficiently inspected in relation to the Homo sapiens (hsa)-microRNA (miR)- 485-5p/ heat shock protein 90 (HSP90) axis, clinically. qRT-PCR was performed to detect lncRNA NNT-AS1 and hsa-miR-485-5p expression levels in 60 Egyptian patients' sera. HSP90 serum level was quantified using Enzyme-linked immunosorbent assay (ELISA).

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Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena, with functional roles in both oncogenic and onco-suppressive pathways. Despite their widespread aberrant expression in a range of human malignancies, the biological activities of the ncRNAs majority are unknown. All showed the involvement of the lncRNA nicotinamide nucleotide transhydrogenase antisense RNA 1 (NNT-AS1).

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