The effect of incentive spirometer training on oromotor and pulmonary functions in children with Down's syndrome.

Objectives: This study investigated the effect of incentive spirometry training on oromotor and pulmonary functions in children with Down's syndrome.

Methods: Thirty-four children with Down's syndrome were randomly divided into two groups; the children were of both sexes and aged between 6 and 12 years. Group A received only oromotor exercises, while Group B received oromotor exercises and incentive spirometry training.

Endobronchial injection of botulinum toxin for the reduction of bronchial hyperreactivity induced by methacholine inhalation in dogs.

Background: Airway smooth muscle contraction causes bronchial constriction and is the main cause of bronchospasm in response to stimulants in asthma patients. In this pilot study, we tested the possibility of using a commercially available neurotoxin-botulinum toxin A (BTX-A)-to reduce bronchial hyperreactivity in dogs.

Methods: Two bronchoscopic sessions were conducted in 6 healthy mongrel dogs.