Publications by authors named "Nada Ben Lazrek"
Article Synopsis
- The study investigates the frequency of HLA alleles in the central Tunisian population to understand their ethnic origins, as previous anthropological research in this area has been limited.
- Using genotyping on 272 healthy organ donors, the researchers identified and compared HLA alleles and haplotypes with various populations, including Arabs, Berbers, and Europeans, through various genetic analyses.
- The results show that central Tunisians share closer genetic similarities with other Tunisian and North African populations, as well as Iberians, while being more distantly related to sub-Saharan Africans and Eastern Mediterranean groups, despite significant cultural and religious influences from Arab populations.
Introduction: Human Leukocyte Antigen (HLA) system is a highly polymorphic genetic system associated with the prognosis of several infectious diseases. The aim of this study is to investigate the association of HLA polymorphism with the outcome of coronavirus disease 2019 (COVID-19) in Tunisian critically ill patients.
Methods: this retrospective cross-sectional study included 42 consecutive patients hospitalized in intensive care unit (ICU) for COVID-19 in March 2021.