A comprehensive review of biopsy techniques for oculoplastic and orbital surgeons from ophthalmic pathologists' perspective.

This narrative review aims to discuss different modalities for obtaining diagnostic orbital biopsies, compares the available updated methods, and provides recommendations on the choice of technique. It also highlights special precautions in the handling of orbital specimens from various pathologies. A search was performed in PubMed and Google Scholar with no language or study type restriction.

Willingness and Motivation of Saudi Patients with Keratoconus to Participate in Clinical Trials.

Introduction Keratoconus is a bilateral non-inflammatory ectasia, characterized by well-described histopathological changes such as stromal thinning, epithelial iron deposition, and breaks in Bowman's layer. The success of clinical intervention among patients with keratoconus is widely determined by randomized clinical trials, and despite associated difficulties, such trials may improve vision and quality of life. Aim This study aimed to assess the willingness of patients with keratoconus in Saudi Arabia to undergo clinical trials.