Quality of life in Turkish infertile couples and related factors.

Infertility is a major life crisis affecting couples' psychosocial and physical health. We aimed to assess the quality of life in Turkish infertile couples. This cross-sectional survey was carried out in 127 infertile couples admitted to a University Hospital.

Immunohistochemical and ultrastructural analysis of the effect of omega-3 on embryonic implantation in an experimental mouse model.

Objective: Implantation is the first step to a healthy pregnancy. Omega-3 supplementation is common to use during pregnancy, for its antioxidant and membrane stabilising effect. In this study we have aimed to study the effect of Omega-3 supplementation on implantation in a mouse model by immunohistochemical methods and electron microscopic evaluation.

Assessment of serum chemerin, vaspin and omentin-1 levels in patients with polycystic ovary syndrome.

Objective: To determine serum chemerin, vaspin and omentin-1 in overweight and normal weight patients with polycystic ovary syndrome (PCOS) and investigate the possible relationship between these adipokines and metabolic syndrome.

Methods: This cross sectional study enrolled women with PCOS and healthy women. Serum chemerin, vaspin and omentin-1 were assessed by enzyme-linked immunosorbent assay methods.

Rectus abdominis muscle endometriosis.

Endometriosis is characterized by an abnormal existence of functional endometrial tissue outside the uterine cavity, typically occuring within the pelvis of women in reproductive age. We report two cases with endometriosis of the abdominal wall; the first one in the rectus abdominis muscle and the second one in the surgical scar of previous caesarean incision along with the rectus abdominis muscle. Pre-operative evaluation included magnetic resonance imaging.

Leptin expression in proliferative, secretory and hyperplastic endometrial tissues.

Objective: The goal of this study was to detect endometrial leptin expression in proliferative and secretory phases and then to compare the results with that of hyperplastic endometrium.

Material And Methods: Seventeen proliferative, 23 secretory phase and 18 hyperplastic endometrial tissues diagnosed in our hospital between 2002 and 2007 were included in the study. These samples were stained with leptin antibody using an immunohistochemical method.

Oxidative stress but not endothelial dysfunction exists in non-obese, young group of patients with polycystic ovary syndrome.

Objective: To determine if oxidative stress and endothelial dysfunction exist at the same time in a young, non-obese group of patients with polycystic ovary syndrome (PCOS).

Design: Cross-sectional study.

Setting: Celal Bayar University, School of Medicine, Manisa, Turkey.

Two oestrous cycles. Ten days insulin treatment reduced ovarian leptin expression of rat.

Objective: Previous studies have reported a role for insulin in leptin secretion from rat ovarian cells although the time dependent effect of insulin has yet to be obtained. The study aim is to determine the time dependent effect of insulin on leptin staining intensity in the rat ovary.

Methods: Normally cycling rats were investigated in a spontaneous cycle (control, n=6), one cycle with insulin treatment 2 U/day for 5 days (D5) (n=6), and 2 cycles with insulin treatment 2 U/day for 10 days (D10) (n=6) in the Department of Histology and Embryology, Celal Bayar University, Manisa, Turkey, from May 2004 to August 2004.

Effect of insulin on rat ovarian leptin expression by immunohistochemical staining.

Aim: Leptin and insulin may interact in regulating ovarian steroid synthesis. The objective of this study was to investigate immunohistochemical staining of leptin in normal rat ovarian tissues and in rats treated with insulin and insulin plus human chorinoic gonadotropin (hCG).

Methods: Paraffin blocks of rat ovarian tissues from a previous study, in which 18 adult, female Wistar rats with an average weight of 250 g were divided into three groups to receive either saline solution, human insulin (2 U/day) or human insulin (2 U/day) plus hCG (4 U/day) for 4 weeks, were used in this study to compare the effects on leptin staining.

Interleukin-6 levels in hyperemesis gravidarum.

Introduction: Hyperemesis gravidarum (HG) is associated with higher levels of serum beta-hCG levels and hyperthyroidism. Interleukin-6 (IL-6), a pro-inflammatory cytokine, is reported to enhance secretion of beta-hCG from trophoblastic cell line.

Methods: We measured serum levels of IL-6, thyroid hormones and beta-hCG of hyperemetic patients and gestational age-matched controls to search for a difference between the two groups.

Detection of endothelial dysfunction in preeclamptic patients by using color Doppler sonography.

Our goal in this study was to detect endothelial function in normal and preeclamptic patients by using color Doppler sonography and plasma fibronectin levels. The increased ratio of the brachial artery diameter during shear stress, and plasma fibronectin levels were measured in 15 preeclamptic and 11 normal, gestational-age matched pregnant patients. The test was repeated at the postpartum second and sixth weeks in the preeclamptic group.

Tear function changes of postmenopausal women in response to hormone replacement therapy.

Objective: The goal of this study was to search the effect of hormone replacement therapy (HRT) on tear function changes in postmenopausal women.

Methods: Following initial ophtalmic evaluation and tear sample collection, the subjects were given daily 0.625 mg conjugated estrogen, and either continuous combined or cyclic 5 mg medroxyprogesterone acetate was added.

Giant mucinous cystadenocarcinoma: a case report.

We present a mucinous cystadenocarcinoma weighing 10 kg in a postmenopausal woman and the way how we managed the case.

Insulin and oral antidiabetic agents for treatment of polycystic ovary syndrome.

Insulin plays a major role in polycystic ovary syndrome (PCOS). Insulin resistance and resultant hyperinsulinemia stimulate both the ovary and adrenal to produce androgens. Oral antidiabetic agents have been used to alleviate the symptoms and to induce ovulation in women with PCOS.

Rupture of rudimentary horn pregnancy at the 15th week of gestation: a case report.

A patient with acute abdomen at 15th week of gestation underwent an emergency laparatomy. A ruptured rudimentary horn pregnancy was diagnosed, and the rudimentary part including the fetus and the accessories was resected. The mother survived without any complications.