Proton Pump Inhibitors and the Risk of Osseointegrated Dental Implant Failure: A Cohort Study.

Proton pump inhibitors (PPIs) have a negative impact on bone accrual. Because osseointegration is influenced by bone metabolism, this study investigates the association between PPIs and the risk of osseointegrated implant failure. This retrospective cohort study included a total of 1,773 osseointegrated dental implants in 799 patients (133 implants in 58 PPIs users and 1,640 in 741 non-users) who were treated at the East Coast Oral Surgery Clinic in Moncton, Canada, from January 2007 to September 2015.

Antihypertensive Medications and the Survival Rate of Osseointegrated Dental Implants: A Cohort Study.

Purpose: Antihypertensive drugs in general are beneficial for bone formation and remodeling, and are associated with lower risk of bone fractures. As osseointegration is influenced by bone metabolism, this study aimed to investigate the association between antihypertensive drugs and the survival rate of osseointegrated implants.

Materials And Methods: This retrospective cohort study included a total of 1,499 dental implants in 728 patients (327 implants in 142 antihypertensive-drugs-users and 1,172 in 586 nonusers).

Plaque Accumulation Beneath Maxillary All-on-4™ Implant-Supported Prostheses.

Background: Maxillary prostheses supported by four implants, following the All-on-4(™) principles, have become an accepted effective treatment for totally edentulous patients. Maintaining the hygiene of such fixed implant-supported prostheses is challenging.

Purpose: The purpose of this clinical study was to evaluate the distribution of plaque on the fitting surface of All-on-4 fixed prostheses in order to find new strategies for maintaining their hygiene.

Extraction of impacted mandibular third molars: postoperative complications and their risk factors.

Objective: The purpose of this prospective study was to evaluate the incidence of various complications, including alveolitis, infection and paresthesia of the inferior alveolar nerve, in association with removal of impacted mandibular third molars. The relation between these 3 complications and several clinical variables (age, sex, degree of impaction, surgical difficulty and use of oral contraceptives) was also examined.

Materials And Methods: Data were collected prospectively for all patients who underwent extraction of an impacted third molar in a single private dental practice over a 12-month period.

Antiplatelet drugs : is there a surgical risk?

Acetylsalicylic acid has long been the only nonsteroidal anti-inflammatory drug recommended for the treatment and prevention of thromboembolic diseases. More recently, new compounds have been used in patients with vascular diseases. However, these drugs are often associated with longer bleeding times and greater operative risk.