Publications by authors named "Nacef Lilia"

Background: Calcium-pyrophosphate-dihydrate-disease (CPPD) is a crystal-induced arthropathy. The lumbar-spinal involvement is rare and often under-diagnosed. This study aimed to report the case of a lumbar spine CPPD involvement and to perform a systematic review of clinical, imaging features of lumbar involvement in CPPD patients, and treatments that have been implemented.

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Article Synopsis
  • The introduction discusses how biologics have enhanced treatment for spondyloarthritis (SpA), allowing for sustained remission, but there's limited research on optimizing biologics for patients already in remission.
  • The systematic review analyzed 14 studies on tapering biologics for axial SpA and found that patient-tailored dose reductions are generally successful in maintaining low disease activity, with remission rates varying widely.
  • The review concludes that gradual tapering of anti TNF-α therapy is effective for patients in sustained remission, but more homogeneous studies are needed for a better understanding of tapering strategies.
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Tuberculosis arthritis of the ankle accounts for 10% of all cases of osteoarticular tuberculosis (OT). Because of its rarity and insidious symptoms, diagnosing it may be challenging. Furthermore, its imaging findings mimic those of other diseases.

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Purpose Of Review: Intravesical BCG therapy (ivBCG) is a treatment for bladder cancer that complements surgery and prevents tumor progression. Reactive arthritis (ReA) is a rare osteoarticular manifestation that can complicate this treatment. An updated systematic literature review has been investigated to identify clinical, biological, and therapeutic data of this pathology.

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