Publications by authors named "Nabin Kishor Bimali"
Article Synopsis
- Antimicrobial resistance in Enterobacteriaceae is a growing global concern, with a study in Nepal revealing high rates of antibiotic resistance among bacteria found in clinical specimens.
- The study identified that 19.4% of isolates produced AmpC beta-lactamase, 29.6% produced extended spectrum beta-lactamase (ESBL), and 8.5% produced Metallo-beta-lactamase (MBL), with higher rates found in hospitalized patients compared to out-patients.
- The detection of resistant bacteria in out-patients without recent hospital visits suggests that drug-resistant Enterobacteriaceae are spreading in the community, highlighting the urgent need for strategies to combat antibiotic resistance.
Article Synopsis
- The study investigates the prevalence of carbapenemase genes, specifically metallo-beta-lactamase (MBL) and KPC, among bacterial isolates from urine samples in Kathmandu, focusing on the increase in carbapenem resistance.
- Out of 2474 urine samples tested, 19.5% showed bacterial growth, with the majority being E. coli, of which 4.4% were resistant to carbapenems; MHT confirmed 1.7% as carbapenem-resistant.
- The findings revealed a significant presence of carbapenemase-producing isolates, including NDM genes, highlighting the urgent need for molecular diagnostics to improve infection control and combat drug-resistant bacteria.
Background: Diabetic patients are more susceptible to urinary tract infection compared to nondiabetic patients, being the most common uropathogen causing UTI. Unreasonable and incorrect antibiotic prescription for UTI in these patients may induce the development of antibiotic-resistant urinary pathogens resulting in delayed recovery and longer hospitalization. In addition to these, biofilm forming capacity of the pathogen may worsen the problem.
View Article and Find Full Text PDFSwine nasal samples [n = 282] were collected from 12 randomly selected farms around Kathmandu, Nepal, from healthy animals. In addition, wild monkey (Macaca mulatta) saliva samples [n = 59] were collected near temples areas in Kathmandu using a non-invasive sampling technique. All samples were processed for MRSA using standardized selective media and conventional biochemical tests.
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