Community-acquired meningitis in older adults: clinical features, etiology, and prognostic factors.

Objectives: To investigate the epidemiology and outcomes of community-acquired meningitis in older adults.

Design: Retrospective study.

Setting: Participants adults in Houston, Texas, with community-acquired meningitis hospitalized between January 1, 2005, and January 1, 2010 (N = 619; n = 54, 8.

Meningitis with a negative cerebrospinal fluid Gram stain in adults: risk classification for an adverse clinical outcome.

Objective: To derive and validate a risk score for an adverse clinical outcome in adults with meningitis and a negative cerebrospinal fluid (CSF) Gram stain.

Patients And Methods: We conducted a retrospective study of 567 adults from Houston, Texas, with meningitis evaluated between January 1, 2005, and January 1, 2010. The patients were divided into derivation (N=292) and validation (N=275) cohorts.