Cystic fibrosis gene mutations and polymorphisms in Saudi men with infertility.

Background: Some mutations of the cystic fibrosis transmembrane regulator () gene may impair spermatogenesis or cause a congenital absence of the vas deferens that manifests as isolated male infertility.

Objective: Assess the frequency and analyze the spectrum of gene variations in Saudi men with primary infertility.

Design: Prospective, cross-sectional.