Publications by authors named "Nabeel Seedat"

Introduction: Computational models providing accurate estimates of their uncertainty are crucial for risk management associated with decision-making in healthcare contexts. This is especially true since many state-of-the-art systems are trained using the data which have been labeled automatically (self-supervised mode) and tend to overfit.

Methods: In this study, we investigate the quality of uncertainty estimates from a range of current state-of-the-art predictive models applied to the problem of observation detection in radiology reports.

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Wearable electroencephalography devices emerge as a cost-effective and ergonomic alternative to gold-standard polysomnography, paving the way for better health monitoring and sleep disorder screening. Machine learning allows to automate sleep stage classification, but trust and reliability issues have hampered its adoption in clinical applications. Estimating uncertainty is a crucial factor in enhancing reliability by identifying regions of heightened and diminished confidence.

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Generalization – the ability of AI systems to apply and/or extrapolate their knowledge to new data which might differ from the original training data – is a major challenge for the effective and responsible implementation of human-centric AI applications. Current debate in bioethics proposes selective prediction as a solution. Here we explore data-based reasons for generalization challenges and look at how selective predictions might be implemented technically, focusing on clinical AI applications in real-world healthcare settings.

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With the increasing prevalence of machine learning in critical fields like healthcare, ensuring the safety and reliability of these systems is crucial. Estimating uncertainty plays a vital role in enhancing reliability by identifying areas of high and low confidence and reducing the risk of errors. This study introduces U-PASS, a specialized human-centered machine learning pipeline tailored for clinical applications, which effectively communicates uncertainty to clinical experts and collaborates with them to improve predictions.

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