Machine Learning Algorithm-Based Prediction of Diabetes Among Female Population Using PIMA Dataset.

: Diabetes is a metabolic disorder characterized by increased blood sugar levels. Early detection of diabetes could help individuals to manage and delay the progression of this disorder effectively. Machine learning (ML) methods are important in forecasting the progression and diagnosis of different medical problems with better accuracy.

Effect of a home-based exercise program on subsequent falls among community-dwelling older adults with cognitive frailty: A sub-group analysis of a randomized controlled trial.

Objectives: Cognitive frailty is characterized by concurrent physical frailty and mild cognitive impairment and is associated with increased risk of falls. Exercise is an evidence-based strategy to prevent falls, but whether exercise reduces falls in people with cognitive frailty is unknown. We examined the effects of home-based exercise on subsequent falls among community-dwelling older adults with cognitive frailty who have previously fallen.

Impact of halogen⋯halogen interaction on the mechanical motion of a 3D Pb(II) coordination polymer of elusive topology.

Herein, we report the synthesis of a Pb(II) based three-dimensional coordination polymer (3D CP), [Pb(DCTP)] (1) [HDCTP = 2,5-dichloroterephthalic acid] with an unprecedented topology, which exhibits a photomechanical effect wherein crystals show jumping upon UV irradiation. The Pb(II) CP forms a type II Cl⋯Cl interaction, which weakens further upon UV irradiation to resolve the anisotropic mechanical strain. The work presented here could be a beacon to the nascent field of photoactuating smart materials.

Germ Cell Tumor Presenting as a Mesenteric Cyst: a Case Report and Literature Review.

Mesenteric cysts, typically benign and asymptomatic, are incidental findings during abdominal investigations for nonspecific symptoms. Their origin is commonly in the mesentery of the small bowel, mesocolon, or retroperitoneum. This paper reports a rare case of a 22-year-old male with a mesenteric cyst presenting as a right lower abdominal mass.

Correction to 1,2,3-Triazole Tethered Hybrid Capsaicinoids as Antiproliferative Agents Active against Lung Cancer Cells (A549).

[This corrects the article DOI: 10.1021/acsomega.2c03325.

Bioremediation of hydrocarbon by co-culturing of biosurfactant-producing bacteria in microbial fuel cell with FeO-modified anode.

The most common type of environmental contamination is petroleum hydrocarbons. Sustainable and environmentally friendly treatment strategies must be explored in light of the increasing challenges of toxic and critical wastewater contamination. This paper deals with the bacteria-producing biosurfactant and their employment in the bioremediation of hydrocarbon-containing waste through a microbial fuel cell (MFC) with Pseudomonas aeruginosa (exoelectrogen) as co-culture for simultaneous power generation.

A dual-functional 2D coordination polymer exhibiting photomechanical and electrically conductive behaviours.

A photoactive two-dimensional coordination polymer (2D CP) [Zn(4-spy)(bdc)] (1) [4-spy = 4-styrylpyridine and Hbdc = 1,4-benzendicarboxylic acid] undergoes a photochemical [2 + 2] cycloaddition reaction upon UV irradiation. Interestingly, the crystals of 1 show different photomechanical effects, such as jumping, swelling, and splitting, during UV irradiation. In addition, the CP was employed for conductivity measurements before and after UV irradiation current density-voltage characteristics and impedance spectroscopy, which suggest that they are semiconducting in nature and can be used as Schottky diodes.

Impact of Some Toxic Metals on Important ABC Transporters in Soybean ( L.).

In plants, ATP-binding cassette (ABC) transporters facilitate the movement of substrates across membranes using ATP for growth, development, and defense. Soils contaminated with toxic metals such as cadmium (Cd) and mercury (Hg) might adversely affect the metabolism of plants and humans. In this study, a phylogenetic relationship among soybeans' () ATP binding cassette (GmABCs) and other plant ABCs was analyzed using sequence information, gene structure, chromosomal distribution, and conserved motif-domain.

Regulating photosalient behavior in dynamic metal-organic crystals.

Dynamic photoactuating crystals have become a sensation due to their potential applications in developing smart medical devices, molecular machines, artificial muscles, flexible electronics actuators, probes and microrobots. Here we report the synthesis of two iso-structural metal-organic crystals, [Zn(4-ohbz)(4-nvp)] (1) and [Cd(4-ohbz)(4-nvp)] (2) {H4-ohbz = 4-hydroxy benzoic acid; 4-nvp = 4-(1-naphthylvinyl)pyridine} which undergo topochemical [2 + 2] cycloaddition under UV irradiation as well as sunlight to generate a dimerized product of discrete metal-complex [Zn(4-ohbz)(rctt-4-pncb)] {rctt-4-pncb = 1,3-bis(4'-pyridyl)-2,4-bis(naphthyl)cyclobutane} (1') and one-dimensional coordination polymer (1D CP) [Cd(4-ohbz)(rctt-4-pncb)] (2') respectively, in a single-crystal-to-single-crystal (SCSC) process. The Zn-based compound demonstrates photosalient behaviour, wherein crystals show jumping, splitting, rolling, and swelling upon UV irradiation.

Evaluation of Antidiabetic Effect of Luteolin in STZ Induced Diabetic Rats: Molecular Docking, Molecular Dynamics, In Vitro and In Vivo Studies.

Despite the existence of modern antidiabetic medications, diabetes still affects millions of individuals worldwide, with a high death and disability rate. There has been a concerted search for alternative natural medicinal agents; luteolin (LUT), a polyphenolic molecule, might be a good choice, both because of its efficacy and because of it having fewer side effects, compared to conventional medicines. This study aims to explore the antidiabetic potential of LUT in diabetic rats, induced by streptozotocin (STZ; 50 mg/kg b.

OdorTAM: Technology Acceptance Model for Biometric Authentication System Using Human Body Odor.

Body odor is a biometric feature unique to each individual, and it can be used for authentication. However, decision makers must learn about the users' level of acceptance of this technology, as well as their thoughts on the system's features and procedures. In this study, a technology acceptance model (TAM) for body-odor-based biometric techniques named OdorTAM was proposed and validated.

Cu(II)-Based Molecular Hexagons Forming Honeycomb-like Networks Exhibit High Electrical Conductivity.

Four new Cu(II)-based hexagonal complexes with the metallomacrocycle formulae [Cu(5-nip)(3-py)(HO)] (), [Cu(5-nip)(3-Clpy)(HO)] (), [Cu(5-nip)(3-Brpy)(HO)] (), and [Cu(5-nip)(3-Ipy)(HO)] () have been synthesized using 5-nitroisophthalic acid (H5-nip) and pyridine (py)/3-halopyridine (3-Xpy; X = Cl, Br, and I) ligands. The structural features and supramolecular interactions of compounds - have been investigated using the single-crystal X-ray diffraction (SCXRD) technique. Interestingly, the hexagonal complexes undergo hydrogen bonding and π···π stacking interactions to form fascinating two-dimensional (2D) honeycomb-like structures.

Photomechanical effect in Zn(II) and Cd(II) 1D coordination polymers: photosalient to non-salient behaviour.

A Zn(II) based one-dimensional (1D) coordination polymer (CP), [Zn(-1,4-chdc)(4-nvp)] (1) {-1,4-Hchdc = -1,4-cyclohexanedicarboxylic acid and 4-nvp = 4-(1-naphthylvinyl)pyridine}, undergoes a solid-state photochemical [2+2] cycloaddition reaction, accompanied by mechanical motion, wherein crystals show swelling, jumping, splitting and bursting upon UV irradiation, whereas the analogous Cd(II) CP [Cd(-1,4-chdc)(4-nvp)] (2) does not show any such response under UV light, although it undergoes [2+2] photodimerization. The present study can certainly provide the fundamental understanding for designing smart photoactuating materials.

1,2,3-Triazole Tethered Hybrid Capsaicinoids as Antiproliferative Agents Active against Lung Cancer Cells (A549).

A series of novel 1,2,3-triazole derivatives of capsaicin and its structural isomer (new natural product hybrid capsaicinoid) were synthesized by exploiting one-/two-point modification of capsaicin without altering the amide linkage (neck). The newly synthesized compounds were screened for their antiproliferative activity against an NCI panel of 60 cancer cell lines at a single dose of 10 μM. Most of the compounds have demonstrated reduced growth between 55 and 95%, whereas capsaicin () has shown reduced growth between 0 and 24%.

Mitigative effect of biosynthesized SeNPs on cyanobacteria under paraquat toxicity.

Increasing population has resulted in increased food demand. Pesticides like paraquat (PQ) have been used indiscriminately to increase the growth and yield of crops. However, this has adversely affected a wide spectrum of non-target organisms like cyanobacteria that are used as a bio-fertilizer in the rice field.

Emotional responses and coping strategies of medical students during the COVID-19 pandemic.

Objectives: To assess the emotional responses and coping strategies of medical students during the lockdown and social distancing measures implemented during the coronavirus disease -19 (COVID-19) pandemic.

Methods: This cross‑sectional study is based on data collected from undergraduate medical students at the College of Medicine, Alfaisal University Riyadh, Saudi Arabia, during the fall semester of academic year 2020-2021. All the participants completed a self-administered online questionnaire consisting of 3 parts: demographic information, emotional response scale, and 14-item, adapted brief coping orientation to problems experienced inventory to determine the use of avoidant or approach coping strategies.

Apoptosis Inducing 1,3,4-Oxadiazole Conjugates of Capsaicin: Their Antiproliferative and Studies.

A series of 1,3,4-oxadiazole tethered capsaicin derivatives was prepared by using one point modification at the vanillyl-hydroxyl group of capsaicin. All the prepared capsaicinoids were evaluated for their antiproliferative activity against NCI-60 human cancer cell lines at 10 μM. Among the compounds tested, compound exhibited good cytotoxic activity against HCT-116, NCI-H460, and SKOV3 cell lines with IC 8.

Exogenous salicylic acid mediated herbicide (Paraquat) resistance in cyanobacterial biofertilizer Microchaete sp. NCCU-342.

Paddy field farming remains the dominant form of growing rice in modern times as the rice is the staple food for over half the world's population and is closely associated with food security and political stability of many countries. Record increase in rice production have been observed since the start of the Green Revolution. India is one of the largest paddy producer and exporter in the world.

1,3,4-oxadiazole conjugates of capsaicin as potent NorA efflux pump inhibitors of Staphylococcus aureus.

NorA efflux pump pertaining to the major facilitator superfamily (MFS) is known to play a key role in antibiotic and biocide resistance in Staphylococcus aureus (S. aureus). It accounts for the extrusion of antibiotics like fluoroquinolones (e.

Seroprevalence of low avidity anti-Toxoplasma IgG in pregnant women and its relationship with their age and contact with cats.

Toxoplasma gondii is a protozoan parasite that can infect all mammals, serving as intermediate hosts. The cause of congenital toxoplasmosis is transplacental transmission of the parasite to the foetus, resulting in wide range of manifestations from mild chorioretinitis to miscarriage. Its frequency can be reduced by early screening of pregnant women which is based mainly on tests for anti-Toxoplasma antibodies.

Multifunctional Efficacy of Environmentally Benign Silver Nanospheres for Organic Transformation, Photocatalysis, and Water Remediation.

Highly crystalline and monophasic silver nanospheres with a high specific surface area of 57 m/g have been synthesized by an environmentally benign rapid chemical reduction using l-alanine for catalytic transformation, photocatalytic degradation, and bacterial disinfection, which can provide an ample strategy for water remediation. Electron microscopic analysis confirms the spherical morphology of as-prepared silver nanoparticles with an average grain size of 20 nm. Silver nanospheres showed excellent catalytic activity for the catalytic hydrogenation and conversion (95.

Applicability of mobile contact tracing in fighting pandemic (COVID-19): Issues, challenges and solutions.

Contact Tracing is considered as the first and the most effective step towards containing an outbreak, as resources for mass testing and large quantity of vaccines are highly unlikely available for immediate utilization. Effective contact tracing can allow societies to reopen from lock-down even before availability of vaccines. The objective of mobile contact tracing is to speed up the manual interview based contact tracing process for containing an outbreak efficiently and quickly.