Subjective oral symptoms are insufficient predictors of a positive oral food challenge.

Background: Subjective oral symptoms, especially if recurrent, might lead to termination of an oral food challenge (OFC) for fear of a subsequent severe reaction.

Methods: In a single-center retrospective cohort study, oral food challenges to milk, egg, peanut, sesame, or tree nuts performed between January 2016 and January 2018 in patients aged ≥3 years, at the Institute of Allergy, Immunology and Pediatric Pulmonology in Shamir Medical Center, were analyzed. Subjective oral symptoms during the challenge were documented, and their association with the challenge outcome was examined.

Patient Characteristics and Risk Factors for Home Epinephrine-Treated Reactions During Oral Immunotherapy for Food Allergy.

Background: Oral immunotherapy (OIT) is effective in desensitizing food-allergic patients but adverse events limit its applicability.

Objective: To identify risk factors for home epinephrine-treated reactions during the build-up phase of OIT.

Methods: A retrospective cohort study of patients older than 3.