Adult hippocampal neurogenesis (AHN) is crucial for learning, memory, and emotion. Deficits of AHN may lead to reduced cognitive abilities and neurodegenerative disorders, such as Alzheimer's disease. Extensive studies on rodent AHN have clarified the developmental and maturation processes of adult neural stem/progenitor cells.
View Article and Find Full Text PDFObjective: To analyze the patient and visitor workplace violence (PVV) toward health workers (HWs) and identify correlations between worker characteristics, measures against violence and exposure to PVV in COVID-19 pandemic.
Methods: A cross-sectional survey utilizing the international questionnaires in six public tertiary hospitals from Beijing in 2020 was conducted, and valid data from 754 respondents were collected. Multilevel logistic regression models were used to determine the association between independents and exposure to PVV.
Ethnopharmacological Relevance: Physalin B is one of the main active withanolide existed in Physalis alkekengi L. var. franchetii (Mast.
View Article and Find Full Text PDFDiabetes mellitus often results in a number of complications involving impaired brain function, including cognitive deficits and depression. However, the potential mechanisms for diabetes-related cognitive deficits and depression are not fully understood. Neurons in the hippocampal, cortical and amygdala functional regions are more susceptible to damage during hyperglycemia.
View Article and Find Full Text PDFMacrophage migration inhibitory factor (MIF) involves the pathogenesis of atherosclerosis (AS) and increased plasma MIF levels in diabetes mellitus (DM) patients are associated with AS. Here, we have been suggested that MIF could be a critical contributor for the pathological process of diabetes-associated AS by using adenovirus-mediated RNA interference. First, streptozotocin (STZ)-induced diabetic animal model was constructed in 114 apolipoprotein E-deficient mice (apoE-/- mice) fed on a regular chow diet.
View Article and Find Full Text PDFMarek's disease (MD) is a neoplastic and neurodegenerative disease of chickens, which is caused by the Gallid herpesvirus type 2 (GaHV-2). Although vaccination has been used widely in China, MD still occurs frequently. Some molecular epidemiologic studies have shown that Chinese GaHV-2 isolates seem to constitute a separate clade from strains isolated from other regions.
View Article and Find Full Text PDFPremise Of The Study: We isolated and characterized polymorphic microsatellite loci in Cyclobalanopsis glauca (Fagaceae), an evergreen broadleaved monoecious tree, to provide tools for analyzing parentage and mating system.
Methods And Results: Thirteen polymorphic microsatellite markers were developed and tested in three C. glauca populations.
Premise Of The Study: Polymorphic microsatellite primers were developed in the seagrass Zostera japonica to investigate genetic variation and to identify clonal structure. •
Methods And Results: Thirteen polymorphic loci and 23 monomorphic loci were developed in Z. japonica.
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Premise Of The Study: Polymorphic microsatellite primers were developed in the seagrass Halophila ovalis to investigate genetic variation. •
Methods And Results: Ten polymorphic microsatellite loci were developed in Halophila ovalis. The number of alleles per locus ranged from 2 to 12 across 80 H.
Premise Of The Study: Polymorphic microsatellite primers were developed in the vulnerable seagrass Halophila beccarii to investigate genetic variation and provide necessary markers for studying its population genetic structure.
Methods And Results: Six polymorphic and six monomorphic microsatellite loci were developed in H. beccarii.