Chiral core-shell microspheres β-CD-COF@SiO used for HPLC enantioseparation.

Chiral covalent organic frameworks (CCOFs) have potential application in enantioseparation due to their advantages, such as large surface area, abundant chiral recognition sites and good chemical stability in organic solvents. However, the application of CCOFs in high performance liquid chromatography (HPLC) for enantioseparation has been rarely reported because of the shortcomings of CCOFs, such as light weight, irregular shape, and wide particle size distribution. In order to overcome the above shortcomings, a one-pot synthetic method was adopted to prepare a core-shell composite (β-CD-COF@SiO) via the growth of chiral β-CD COF on the surface of amino-functionalized SiO microspheres.

A chiral metal-organic framework core-shell microspheres composite for high-performance liquid chromatography enantioseparation.

The unique features of uniform and adjustable cavities, abundant chiral active sites, and high enantioselectivity make chiral metal-organic frameworks popular as an emerging candidate for enantioselective separation. However, the wide particle size distribution and irregular shape of as-synthesized metal-organic frameworks result in low column efficiency, undesired chromatographic peak shape, and high column backpressure of such metal-organic frameworks packed columns. Herein, we report the fabrication of chiral core-shell microspheres [Cu (d-Cam) (4,4'-bpy)] @SiO composite for high-performance liquid chromatography enantioseparation to overcome the above-mentioned problems.

A label-free and sensitive photoluminescence sensing platform based on long persistent luminescence nanoparticles for the determination of antibiotics and 2,4,6-trinitrophenol.

The rapid detection of pollutants with high sensitivity and selectivity is of considerable significance for security screening, environmental safety, and human health. In this study, we prepared persistent luminescence nanoparticles (PLNPs) and constructed a label-free sensor for sensitive and selective detection of pollutants in real samples and test papers. Following excitation, PLNPs could store absorbed light energy and release it in the form of luminescence.