Polydeoxynucleotide-Loaded Visible Light Photo-Crosslinked Gelatin Methacrylate Hydrogel: Approach to Accelerating Cartilage Regeneration.

Articular cartilage faces challenges in self-repair due to the lack of blood vessels and limited chondrocyte concentration. Polydeoxyribonucleotide (PDRN) shows promise for promoting chondrocyte growth and cartilage regeneration, but its delivery has been limited to injections. Continuous PDRN delivery is crucial for effective cartilage regeneration.

Controlling Long-Term Plasticity in Neuromorphic Computing Through Modulation of Ferroelectric Polarization.

Electrolyte-gated transistors (EGTs) have significant potential for neuromorphic computing because they can control the number of ions by mimicking neurotransmitters. However, fast depolarization of the electric double layer (EDL) makes it difficult to achieve long-term plasticity (LTP). Additionally, most research utilizing organic ferroelectric materials has been focused on basic biological functions, and the impact on nonvolatile memory properties is still lacking.

Is there a sexual difference in the relationship between sociodemographic information and the unmet dental care needs of disabled adults? An analysis from a national survey on persons with disabilities.

Background: Health status and health care utilization in people with disabilities are more likely to be poorer than those without disabilities. Previous studies showed that there were gaps in health-related conditions by sociodemographic information and gender but the association between these factors was not explained. This study aims to analyze the relationship between sociodemographic information and the unmet dental care needs of people with disabilities and explore the effect of sex within this relationship.

Necessity of strengthening the current clinical regulatory for companion diagnostics: An institutional comparison of the FDA, EMA, and MFDS.

Companion diagnostics (CDx), which is essential in precision medicine, is changing to a personalized treatment approach. CDx is a test that identifies patients who can benefit from a specific drug and those who experience side effects of drugs for safe and effective treatment. Conversely, when CDx has inadequate diagnostic performance or has not been adequately validated in a particular treatment, treatment prediction based on diagnostic results is not possible.

Breeding of Penta Null Soybean [ (L.) Merr.] for Five Antinutritional and Allergenic Components of Lipoxygenase, KTI, Lectin, 7S α' Subunit, and Stachyose.

Soybean [ (L.) Merr.] is an excellent source of protein, oil, carbohydrates and many other bioactive ingredients for humans.