Direct observation of carbon dioxide adsorption and binding at the air/aqueous interface.

Carbon dioxide removal (CDR) involves reducing carbon dioxide (CO₂) concentrations. Developing new technologies and enhancing existing ones for extracting and converting CO₂ are ongoing areas of research. In all these technologies, the movement of CO molecules through an interface is a common process.

Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer.

There is a growing demand for chimeric antigen receptor (CAR) -T cells for clinical trials. Consequently, new centers capable of manufacturing advanced therapy medicinal products (ATMPs) are needed. In this study, we established a good manufacturing practice -compliant manufacturing process and phase-appropriate analytics for a novel autologous CD19-targeted CAR T-cell product, 19-FiCART.

Technetium and Rhenium Auto-reduction, Polymerization and Lability towards Group VII Polyoxometalate Chemistry.

Group VII Tc and Re have long been studied to develop both radiopharmaceuticals and technologies for nuclear materials management. Fundamental research has targeted understanding this periodic table crossroads where polyoxometalates meets metal-metal bonded complexes. Here we have isolated green hygroscopic and metastable crystals of (Re)(Re)(OH)(O)⋅HO (Re-green, tet=tetrahedral, oct=octahedral), determined by single-crystal x-ray diffraction.

Machine Learning and Deep Learning Models for Automated Protocoling of Emergency Brain MRI Using Text from Clinical Referrals.

Purpose To develop and evaluate machine learning and deep learning-based models for automated protocoling of emergency brain MRI scans based on clinical referral text. Materials and Methods In this single-institution, retrospective study of 1953 emergency brain MRI referrals from January 2016 to January 2019, two neuroradiologists labeled the imaging protocol and use of contrast agent as the reference standard. Three machine learning algorithms (Naïve Bayes, support vector machine, and XGBoost) and two pretrained deep learning models (Finnish BERT and GPT-3.

Aqueous Zr/Hf-Oxo Cluster Speciation and Separation.

Many industrial separations of chemically-similar elements are achieved by solvent extraction, exploiting differences in speciation and solubility across aqueous-organic interfaces. We recently identified [OM(OH)(SCN)] (OM, M=Zr/Hf) tetrahedral oxoclusters as the main species in industrial processes that produce nuclear-grade Zr and Hf from crude ore. However, isostructural/isoelectronic OM-oxoclusters do not explain selective extraction of Hf into the organic phase.

Correction: Huhtanen et al. Discrepancies between Radiology Specialists and Residents in Fracture Detection from Musculoskeletal Radiographs. Diagnostics 2023, , 3207.

Regarding our publication, entitled "Discrepancies between Radiology Specialists and Residents in Fracture Detection from Musculoskeletal Radiographs" [...

Imaging Outcomes of MRI After CT in Pediatric Spinal Trauma: A Single-center Experience.

Background: Imaging has an essential role in the diagnostic workup of suspected pediatric spinal trauma. The most suitable imaging method is still being debated and needs to be considered regarding the patient, injury, and local resources. Magnetic resonance imaging (MRI) is often performed after computed tomography (CT) in case of neurological symptoms or suspected ligamentous disruption.

Structural and Physical Properties of Two Distinct 2D Lead Halides with Intercalated Cu(II).

Transition metal cation intercalation between the layers of two-dimensional (2D) metal halides is an underexplored research area. In this work we focus on the synthesis and physical property characterizations of two layered hybrid lead halides: a new compound [Cu(OC-CH-NH)]PbBr and the previously reported [Cu(OC-(CH)-NH)]PbBr. These compounds exhibit 2D layered crystal structures with incorporated Cu between the metal halide layers, which is achieved by combining Cu(II) and lead bromide with suitable amino acid precursors.

Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs.

The challenge of transforming organized DNA structures into their metallized counterparts persists in the scientific field. In this context, utilizing DNA molecules modified with 7-deazapurine, provides a transformative solution. In this study, we present the solution structure of a DNA duplex that can be transformed into its metallized equivalent while retaining the natural base pairing arrangement through the creation of silver-modified Watson-Crick base pairs.

Electronic Structure and CO Reactivity of Group IV/V/VI Tetraperoxometalates.

Tetraperoxo metal complexes are a category of dioxygen compounds with novel properties. One of their underconsidered applications is in direct air capture (DAC) reactions, whose study is of great interest in order to slow the effects of climate change. Through computational modeling, the present work considers a family of tetraperoxometalate complexes of the form [M(O)] that capture atmospheric CO to produce [MO(O)(CO)] and O.

Accuracy of Intra-Axial Brain Tumor Characterization in the Emergency MRI Reports: A Retrospective Human Performance Benchmarking Pilot Study.

Demand for emergency neuroimaging is increasing. Even magnetic resonance imaging (MRI) is often performed outside office hours, sometimes revealing more uncommon entities like brain tumors. The scientific literature studying artificial intelligence (AI) methods for classifying brain tumors on imaging is growing, but knowledge about the radiologist's performance on this task is surprisingly scarce.

Circular dichroism of relativistically-moving chiral molecules.

Understanding the impact of the relativistic motion of a chiral molecule on its optical response is a prime challenge for fundamental science, but it also has a direct practical relevance in our search for extraterrestrial life. To contribute to these significant developments, we describe a multi-scale computational framework that combines quantum chemistry calculations and full-wave optical simulations to predict the chiral optical response from molecules moving at relativistic speeds. Specifically, the effect of a relativistic motion on the transmission circular dichroism (TCD) of three life-essential biomolecules, namely, B-DNA, chlorophyll a, and chlorophyll b, is investigated.

Risk factors for infection at the saphenous vein harvest site after coronary artery bypass grafting surgery: a retrospective cohort study.

Introduction: Surgical site infection after saphenous vein harvest is common, with reported leg wound infection rates ranging from 2 to 24%. There have been few investigations into sex-related differences in complication rates. Moreover, varied effects of smoking have been reported.

Uranyl-Tc(VII)/Tc(V) hybrid clusters.

Pertechnetate (TcO), reduced Tc, and actinides co-exist in spent nuclear fuel and legacy wastes. They co-transport in fuel reprocessing and waste disposal scenarios, necessitating an understanding of co-speciation. Here, we report five new molecular cluster/framework structures with pentameric and tetrameric uranyl building units decorated by TcO/ReO oxoanions, or fused with the reduced technetyl cation Tc(V)O.

Polarization-dependent effects in vibrational absorption spectra of 2D finite-size adsorbate islands on dielectric substrates.

In the last few years, infrared reflection-absorption spectroscopy (IRRAS) has become a standard technique to study vibrational excitations of molecules. These investigations are strongly motivated by potential applications in monitoring chemical processes. For a better understanding of the adsorption mechanism of molecules on dielectrics, the polarization-dependence of an interaction of infrared light with adsorbates on dielectric surfaces is commonly used.

The Role of Alkalis in Orchestrating Uranyl-Peroxide Reactivity Leading to Direct Air Capture of Carbon Dioxide.

Spectator ions have known and emerging roles in aqueous metal-cation chemistry, respectively directing solubility, speciation, and reactivity. Here, we isolate and structurally characterize the last two metastable members of the alkali uranyl triperoxide series, the Rb and Cs salts (Cs-U and Rb-U). We document their rapid solution polymerization via small-angle X-ray scattering, which is compared to the more stable Li, Na and K analogues.

Cerium Nanophases from Cerium Ammonium Nitrate.

Ceria nanomaterials with facile Ce redox behavior are used in sensing, catalytic, and therapeutic applications, where inclusion of Ce has been correlated with reactivity. Understanding assembly pathways of CeO nanoparticles (NC-CeO) in water has been challenged by "blind" synthesis, including rapid assembly/precipitation promoted by heat or strong base. Here, we identify a layered phase denoted with a proposed formula Ce(OH)(NO)·HO ( ≈ 2.

Utility of brain imaging in pediatric patients with a suspected accidental spinal injury but no brain injury-related symptoms.

Purpose: Imaging is the gold standard in diagnosing traumatic brain injury, but unnecessary scans should be avoided, especially in children and adolescents. Clinical decision-making rules often help to distinguish the patients who need imaging, but if spinal trauma is suspected, concomitant brain imaging is often conducted. Whether the co-occurrence of brain and spine injuries is high enough to justify head imaging in patients without symptoms suggesting brain injury is unknown.

Older women's perceptions of HPV self-sampling and HPV-sampling performed by a midwife - a phenomenographic study.

Background: Cervical cancer is a global disease and it is well established that cervical cancer is caused by human papillomavirus (HPV). In Sweden self-sampling for HPV is now used as a complement to sampling performed by a midwife. However, there is a lack of knowledge on how older women perceive the self-sampling compared to the sampling performed by a midwife.

Plutonium and Cerium Perrhenate/Pertechnetate Coordination Polymers and Frameworks.

Spent nuclear fuel (SNF) contains transuranic and lanthanide species, which are sometimes recovered and repurposed. One particularly problematic fission product, TcO, hampers this recovery via coextraction with high valence metals, perhaps by complexation during aqueous reprocessing of SNF. There is limited molecular-level knowledge concerning the coordination chemistry between TcO or its well-known surrogate ReO and transuranic/lanthanide species.