An Evaluation of Iloperidone for Mania in Bipolar I Disorder.

Objective: To review the efficacy of iloperidone for mania associated with bipolar I disorder and discuss its safety profile (eg, QTc prolongation, orthostatic hypotension, and metabolic adverse effects).

Data Sources: Literature was identified using PubMed (1966-September 2024), OVID (1984-November 2024), and clinicaltrials.gov.

Content analysis of perceptions of combined pharmacobehavioral treatment for American Indian people with opioid use disorder.

Objective: Both opioid misuse and overdose mortality have disproportionately impacted the American Indian population. Although medications for opioid use disorder, such as buprenorphine (BUP-NX), are highly effective in reducing overdose mortality, questions have been raised about the cultural acceptability of Western medical approaches in this population. Understanding patients' desired recovery pathways can lead to more culturally appropriate, patient-centered, and effective approaches to opioid use disorder (OUD) treatment.

Barriers and Facilitators to Vaccine Equity Amidst the COVID-19 Vaccine Rollout in the United States.

State and local health departments were responsible for ensuring equitable distribution of the COVID-19 vaccine. This qualitative study aimed to identify the challenges, strategies, disappointments, and successes in achieving equity for hard-to-reach and at-risk populations. Using a purposive sampling strategy, 16 individuals affiliated with health departments across nine states, each holding leadership roles in vaccine distribution, were interviewed between late 2021 and mid-2022.

Risk of adverse birth outcomes and birth defects among women living with HIV on antiretroviral therapy and HIV-negative women in Uganda, 2015-2021.

Introduction: We assessed the risk of adverse pregnancy and birth outcomes and birth defects among women living with HIV (WLHIV) on antiretroviral therapy (ART) and HIV-negative women.

Methods: We analyzed data on live births, stillbirths, and spontaneous abortions during 2015-2021 from a hospital-based birth defects surveillance system in Kampala, Uganda. ART regimens were recorded from hospital records and maternal self-reports.

Identifying Settler Colonial Determinants of Indigenous Health Within the United States: A Discursive Paper.

Aim(s): This discursive article aims to examine how systemic factors (both) reproduce the structure of settler colonialism and influence health outcomes among Indigenous peoples in the United States through settler colonial determinants of Indigenous health (SCDoIH).

Design: Discursive paper.

Methods: This discursive paper demonstrates how settler colonialism and health relate to each other within a nursing context.

Innovative clearance data model for demining operational data collection: Insights from field trials in Zimbabwe.

From September 2023 to March 2024 a field trial on a live manual demining site was conducted to test a new and innovative approach for the collection and analysis of operational data. The approach, titled the Clearance Data Model, involved the collection of sixty-six data attributes for each mine found. For the first time the mine itself would become the accountable unit of demining data, against which an expanded range of relevant attributes particular to that specific mine would be recorded.

Can Medical Licensing Boards Swing the Pendulum Towards Judicious Opioid Prescribing Practices?

In the initial wave of the opioid crisis, uninformed prescribing practices and lax oversight were the drivers of opioid addiction and death. Although opioid prescriptions have decreased by 44.4 percent between 2011-2020, the number of deaths linked to prescription opioids has decreased only marginally.

Diabetes-specific family functioning typology associated with intervention engagement and effects: secondary analyses from a randomized controlled trial.

Background: Observationally, family and social support are important for optimal diabetes self-management; however, interventions targeting family/social support have not consistently been effective. A novel, diabetes-specific family functioning typology offers the opportunity to classify types of baseline family functioning to determine for whom family interventions may be effective.

Purpose: We examined the effects of an intervention by baseline type of family functioning post hoc, to inform differential benefit from interventions.

Daily glucose variability is associated with intrahepatic fat content, β cell sensitivity, and biomarkers of glycolysis in youth with obesity.

Objective: Pediatric obesity is associated with insulin resistance, which, in turn, impacts glucose and lipid metabolism. This study sought to assess how glucose variability relates to intrahepatic fat content, β cell insulin sensitivity, and glycolysis in youth with obesity.

Methods: A total of 27 youth with obesity (11 girls, BMI percentile, median [25th-75th percentiles]: 99.

An Ecological Momentary Assessment and Intervention Tool for Memory in Chronic Traumatic Brain Injury: Development and Usability of Memory Ecological Momentary Intervention.

Background: Memory and learning deficits are among the most impactful and longest-lasting symptoms experienced by people with chronic traumatic brain injury (TBI). Despite the persistence of post-TBI memory deficits and their implications for community reintegration, memory rehabilitation is restricted to short-term care within structured therapy sessions. Technology shows promise to extend memory rehabilitation into daily life and to increase the number and contextual diversity of learning opportunities.

Dual nitrogen and phosphorus reductions are needed for long-term mitigation of eutrophication and harmful cyanobacterial blooms in the hydrologically-variable San Francisco Bay Delta, CA.

Cyanobacterial harmful algal blooms (CyanoHABs) are a major concern for water quality, public health and viability of aquatic ecosystems. Increased inputs of nutrients, i.e.

Multisystem inflammatory syndrome in children (MIS-C) cases by vaccination status in California.

Multisystem inflammatory syndrome in children (MIS-C) is a rare condition occurring after SARS-CoV-2 infection in children under 21 years of age. Children (5-17 years) with MIS-C meeting the Centers for Disease Control (CDC) case definition were reported via California's passive disease surveillance system. Incidence of MIS-C was compared in unvaccinated and Pfizer-BioNTech vaccinated children aged 12-17 and 5-11 years.

The Transition from Letter Grading to Modified Pass-Fail Grading at a College of Veterinary Medicine: A Narrative Inquiry of Student Experiences.

Compared with traditional letter grading, pass/fail grading is an assessment approach that can alter the educational environment and enhance student wellbeing without compromising education quality. Little is known about the experiences of students during the transition from traditional grading to pass/fail grading. The onset of the COVID-19 pandemic resulted in an abrupt move to modified pass-fail (MPF) grading at North Carolina State University College of Veterinary Medicine (NCSU-CVM), followed by a decision to permanently adopt MPF grading for the entire core pre-clinical doctor of veterinary medicine (DVM) curriculum.

The Role of Body Mass Index on Physical Activity, Symptoms, and Related Outcomes Following Pediatric Concussion.

Objective: To determine the step count and self-reported activity levels for obese and nonobese pediatric patients following concussion and predict self-reported symptoms, quality of life, and psychological health over time.

Study Design: Participants completed the Post-Concussion Symptom Scale (PCSS), Pediatric Quality of Life (PedsQL), and Behavioral Symptom Inventory-18 (BSI-18) at an initial visit (<72 hours), 3-5 days postinjury, 10-18 days postinjury, and 1 and 2 months postinjury. Physical activity data (eg, step count) were collected via a commercial actigraph.

Outcomes after Traumatic Brain Injury with and Without Computed Tomography.

Our recent improved understanding of traumatic brain injury (TBI) comes largely from cohort studies of TBI patients with indication for computed tomography (CT). Using CT head as an inclusion criterion may overestimate poor outcomes after TBI with Glasgow Coma Scale (GCS) 13-15. We aimed to compare outcomes after TBI in adults who had a head CT scan (with negative findings) versus those who had no CT when presenting to an emergency department.

Exploring Facilitators and Barriers to STD/STI/HIV Self-Testing Among College Students in the United States: A Scoping Review.

Background: HIV affects 1.2 million Americans, with 20% of new diagnoses being 13 to 24-year-olds. Young adult college students are more likely than the general population of 18 to 24-year-olds in the U.

Making sense together: dance improvisation as a framework for a collaborative interdisciplinary learning processes.

This editorial outlines the outcome of an interdisciplinary session on collective sense-making through dance improvisation, which took place during the 'Neural and Social Bases of Creative Movement' workshop. We argue that joint improvisation practices place the scientist in a privileged position to reveal the nature of cognitive and creative behaviors.