Ultrasound examination with contrast in the diagnosis of inflammatory bowel disease. The results of the pilot study.

Aim: Assessment of diagnostic significance of informativeness and security of ultrasonography with contrast enhancement drug SonoVue in the diagnosis of Crohn's disease (CD) and ulcerative colitis (UC).

Materials And Methods: The pilot conducted a prospective study which involved 15 patients with inflammatory bowel disease (IBD). All patients gave written consent to participate in the study and processing of personal data.

[The validation of the adequacy of chemotherapy in bladder tuberculosis based on a study of bacteriostatic activity].

Study of the bacteriostatic activity (BA) of the blood, urine and tissue of the tuberculosis-affected urinary bladder after the administration of two tuberculostatic combinations (isoniazid + cycloserine and isoniazid + rifampicin) has demonstrated the difference in the BA curves that were formed in the above media. Use of isoniazid + cycloserine gives rise to a high BA level by 6-9 h with further gradual decrease of the parameters. The combination of isoniazid + cycloserine produces a typical double-humped curve with titre prolongation.

[The tuberculin-transamidinase test--a new method for the diagnosis of renal tuberculosis].

The possible use of the provocative standard test with subcutaneous administration of tuberculin combined with determination of the activity of transamidinase, a renal specific enzyme, in the serum and urine before and 24, 48, 72 and 96 hours after administration of tuberculin was studied for the first time in 63 patients with a purpose of diagnosing nephrophthisis. It was shown that a 2-fold or higher increase in the transaminidase activity in response to subcutaneous administration of 50 TU during the period from 24 to 72 hours could serve as a sign of nephrophthisis.