Publications by authors named "N Zinyakatira"

Article Synopsis
  • Verbal autopsy (VA) helps find out how people died when they weren't in a hospital, but it's hard to use it in official death records.
  • In South Africa, researchers talked to families of people who died to collect information about causes of death in 2017/18.
  • They found that while they could gather useful info, there were still challenges in getting enough people to participate, highlighting the need for better systems to record deaths.
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Article Synopsis
  • * A study in Cape Town, South Africa showed seroprevalence of SARS-CoV-2 rose from 39.19% in July 2020 to 67.8% by November 2021, with poorer communities experiencing higher rates and mortality.
  • * Seropositivity before the Omicron wave offered strong protection against severe disease, suggesting that effective seroprevalence research is essential for understanding true infection rates and directing public health interventions.
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Background: Multi-drug or rifamycin-resistant tuberculosis (MDR/RR-TB) is an important public health concern, including in settings with high HIV prevalence. TB drug resistance can be directly transmitted or arise through resistance acquisition during first-line TB treatment. Limited evidence suggests that people living with HIV (PLHIV) might have an increased risk of acquired rifamycin-resistance (ARR).

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Background: The COVID-19 pandemic resulted in the implementation of strict public health and social measures (PHSMs) (including mobility restrictions, social distancing, mask-wearing and hand hygiene), limitations on non-essential healthcare services, and public fear of COVID-19 infection, all of which potentially affected transmission and healthcare use for other diseases such as lower respiratory tract infections (LRTIs).

Objective: To determine changes in LRTI hospital admissions and in-facility mortality in children aged <5 years in the Western Cape Province during the pandemic.

Methods: We conducted a retrospective analysis of LRTI admissions and in-facility deaths from January 2019 to November 2021.

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Introduction: While a large proportion of people with HIV (PWH) have experienced SARS-CoV-2 infections, there is uncertainty about the role of HIV disease severity on COVID-19 outcomes, especially in lower-income settings. We studied the association of mortality with characteristics of HIV severity and management, and vaccination, among adult PWH.

Methods: We analysed observational cohort data on all PWH aged ≥15 years experiencing a diagnosed SARS-CoV-2 infection (until March 2022), who accessed public sector healthcare in the Western Cape province of South Africa.

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