[The lipid peroxidation indices of hypertension patients undergoing combined therapy with anaprilin, korinfar and hypothiazide].

Lipid peroxidation (LPO) products and activity of antioxidant defense (AOD) were evaluated in the whole blood and red cells of 78 patients with hypertension stage II given anapriline, corinfar and hypotiazid. Combined therapy with anapriline and hypotiazid (80-120 mg/day and 50 mg/day, respectively) diminishes concentrations of diene conjugates and malonic dialdehyde (MDA) in blood though LPO parameters after the treatment exceeded those of healthy subjects. Native antioxidants content and activity of antioxidant enzymes glutathione peroxidase and superoxide dismutase increased.

[Changes in the central and intracardiac hemodynamics of patients with rheumatoid arthritis (an echocardiographic study)].

It was found that rheumatoid arthritis patients with clinical signs of cardiac involvement showed significant changes of the central and intracardiac hemodynamics that were characterized by suppression of the contractile and pumping function of the left ventricle as compared with patients showing no heart involvement. The authors describe in detail special treatment of RA patients with cardiac involvement.