Publications by authors named "N Yumusak"
The effect of nicardipine on the zone of stasis in burns: An experimental rat model.
Ulus Travma Acil Cerrahi Derg
March 2025
Background: The zone of stasis in burns is particularly vulnerable to progressive ischemia, making it a critical target for therapeutic interventions. Preventing damage in this zone is essential, as its viability can be preserved with adequate perfusion. Recognizing this, we aimed to investigate the systemic effects of nicardipine, a calcium channel blocker with vasodilatory properties, on the stasis zone in an experimentally induced burn model in rats.
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- Ischemia-reperfusion (IR) injury negatively impacts the ovaries, and this study examined the potential benefits of Tarantula cubensis extract (TCE) on this condition in female rats.
- The rats were divided into seven groups, where some received TCE or ethanol before or after being subjected to ischemia (lack of blood flow) and reperfusion (restoration of blood flow) while others acted as controls.
- Results showed that TCE treatment improved the histopathological condition of the ovaries, particularly when administered before ischemia, despite not significantly lowering certain oxidative stress markers; additionally, inflammatory cytokine levels decreased with TCE treatment.
Article Synopsis
- * Patients undergoing surgery for DDH were grouped based on different factors like age and family history, with the research focusing on the histological features and the presence of specific proteins (MMP-2, MMP-9, and ADAMTS-7).
- * Findings show that the ligamentum teres has signs of moderate inflammation and other changes, and that the levels of MMP-2, MMP-9, and ADAMTS-7 are positively linked to these tissue changes
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- A study was done to see how Dexmedetomidine could help damaged tear glands in rats after they received a high dose of radioiodine treatment.
- The study involved three groups of rats: one group got a fake treatment, another group got radioiodine only, and the last group got both radioiodine and Dexmedetomidine.
- Results showed that Dexmedetomidine helped reduce damage and inflammation in the tear glands caused by the radioiodine treatment, making them healthier again.
Article Synopsis
- This study investigates the effects of pitavastatin on nerve injury in rats, focusing on electrophysiological, scintigraphic, and histopathological outcomes.
- A total of 30 Wistar albino rats were divided into three groups to evaluate the impact of pitavastatin on nerve injury over 21 days, using various analysis methods for assessment.
- Results indicated significant differences in gait parameters and histopathological measures among the groups, suggesting that pitavastatin may aid in nerve regeneration and recovery of motor function in cases of sciatic nerve injury.*