Electrochemical Biosensors for Express Analysis of the Integral Toxicity of Polymer Materials.

Biosensors based on an oxygen electrode, a mediator electrode, and a mediator microbial biofuel cell (MFC) using the bacteria B-1280 were formed and tested to determine the integral toxicity. bacteria exhibited high sensitivity to the toxic effects of phenol, 2,4-dinitrophenol, salicylic and trichloroacetic acid, and a number of heavy metal ions. The system " bacteria-ferrocene-graphite-paste electrode" was superior in sensitivity to biosensors formed using an oxygen electrode and MFC, in particular regarding heavy metal ions (EC of Cr, Mn and Cd was 0.

[Primary vitrectomy in the treatment of retinopathy of prematurity with unfavorable progression].

Purpose: The study aims to determine the indications and evaluate the results of primary vitrectomy in unfavorable progression of stage III active retinopathy of prematurity (ROP).

Material And Methods: The control group consisted of 17 patients (28 eyes) with unfavorable progression of stage III ROP, who had the disease progress after coagulation of the avascular retina and underwent the second stage of treatment - vitrectomy. The main group consisted of 5 patients (10 eyes) with unfavorable progression of stage III ROP, who underwent primary vitrectomy.

[Vaginal leiomyosarcoma in pregnancy].

The article presents a rare clinical observation of a vaginal tumor detected during pregnancy, which prevented delivery through the natural birth canal and caused a cesarean section at full term. According to the primary biopsy at 34 weeks, neurofibroma was diagnosed. In the postpartum period, due to profuse bloody discharge, the patient was admitted to the Moscow Regional Research Institute of Obstetrics and Gynecology for surgical treatment, where, according to the results of a morphological study of the removed tumor, vaginal leiomyosarcoma was diagnosed.

Efficacy of combined immunosuppression with or without eltrombopag in children with newly diagnosed aplastic anemia.

We compared the efficacy and safety of eltrombopag (ELTR) combined with immunosuppressive therapy (IST) and IST alone in treatment-naïve children with severe (SAA) and very severe (vSAA) aplastic anemia. Ninety-eight pediatric patients were randomized to receive horse antithymocyte globulin (hATG) and cyclosporin A (CsA) with (n = 49) or without (n = 49) ELTR. The primary endpoint was the overall response rate (ORR) at 4 months.

[ASSESSMENT OF PATIENT SATISFACTION WITH THE MEDICAL ORGANIZATION AND ITS SERVICES].

The relevance of the problem under study is due to the fact that the medical organization must be aware of the target patient: to know who he is, how and why he wants to receive a particular medical service. All the information received and its analysis will allow us to develop a real scheme of mutually beneficial communication, convenient for each of the parties-the medical organization and the patient, which will allow us to reveal the weaknesses in the work and respond to them in a timely manner. The purpose of the study: to form an assessment of the patient's satisfaction with the medical organization and its services, taking into account the interest, feelings, purpose, arguments and thoughts that appear in the patient from the moment of the first contact with the clinic, with the display of the point of contact in graphic form, in order to minimize all possible obstacles in his route to receiving quality medical services and increasing the economic efficiency of the clinic.