[Orthostatic reactions in prognosis of the risks of arterial hypertension as a component of metabolic syndrome].

It was shown that parameters of metabolic syndrome as predictors of lethal vascular outcomes of arterial hypertension (AH) in Belarus are significantly different fiom those proposed in WHO recommendations (1999). The glucose level of informative value in WHO recommendations is 6.1 mmol/l versus 5.

[Changes in the fat-acid spectrum of high-density lipoproteins as observed in men and women with acute appendicitis].

Differences in the reaction of the fat-acid spectrum of high-density lipoproteins (HDLP and HDLP3) and ethers of transfer-protein cholesterol (ETPC) as well as in the activity of lecithin cholesterin acetyltransferase and the content of cholesterol were compared for male and female patients (of the second mature age) with appendicitis. It was concluded that the female patients with appendicitis had, versus healthy women of the same age, a lower share of poly-unsaturated fat acids (PUFA) in the HDLP content and, possibly, a compensatorily intensified activity of the delta9-desaturase system; the changes were concomitant with a reduced functional HDLP activity. Within the discussed age span, the female patients with appendicitis had, versus the male patients, a more drastically reduced content of PUFA in HDLP, which was accompanied by a more intense modification of their functional activity with an active metabolism of PUFA (possibly of the omega9-row) due to ETPC.

Changes in the blood lipid-transporting system in rats over the first day of experimental peritonitis.

Changes in the lipid spectrum of blood plasma and composition of high-density lipoproteins in outbred albino rats were studied during early stages of experimental peritonitis. We revealed an increase in lecithin:cholesterol acyltransferase activity, activation of lipolytic production of high-density lipoproteins from very-low-density lipoproteins, and substitution of arachidonic acid in cholesterol esters for dihomo-gamma-linoleic acid 7 h after induction of peritonitis. After 24 h the protein composition and functional activity of high-density lipoproteins was modified and the amount of saturated fatty acids in cholesterol esters increased.

Effect of polyunsaturated phosphatidyl-choline on lipid transport system in alcoholic liver injury.

The aim of this study was to determine whether serum lipid composition and lipolytic activities in alcoholinduced liver dystrophy were modified by the co-administration of polyunsaturated phosphatidylcholine (PPC). Chronic alcohol intoxication was induced in rats by intragastric ethanol administration of 3.5 g/kg body weight per day over 56 days.

[Effect of polyunsaturated phosphatidylcholine on the activity of antioxidant and lipolytic enzymes in alimentary hypercholesterolemia in irradiated rats].

A high-cholesterol diet containing 3.5% cholesterol, 0.2% methyl thiouracil and 20% of heated sunflower-seed oil caused an increase in the content of cholesterol, triacylglycerols, diene conjugates and in the activity of phospholipase A2 in rat liver and of serum total cholesterol and cholesterol of low density lipoproteins, and a decrease in the activity of hepatic cholesterol esterase, in the fractional activity of lecithin:cholesterol acetyl transferase (LCAT), in the activity of the enzymes involved in the lipolytic transformation of lipoproteins and in the serum levels of very low density lipoprotein cholesterol.