Tocilizumab for Cystoid Macular Edema Secondary to Immune Recovery Uveitis in a Patient with Contraindications to Long-Term Systemic Corticosteroid.

: To report a case of cystoid macular edema (CME) secondary to immune recovery uveitis (IRU) in a patient with previous history of cytomegalovirus (CMV) retinitis and leukemia, which was successfully treated with tocilizumab (TCZ), an interleukin-6 (IL-6) receptor antagonist. : The clinical records of the case were reviewed, focusing on demographics, image findings, and clinical course. : A 17-year-old female with a past medical history of T-cell acute lymphoblastic leukemia (T-ALL) undergoing chemotherapy for two years presented with active CMV retinitis.

Hybrid nanostructures of urchin-like MnCoO micro flowers on N, B co-doped rGO for electrochemical determination of paracetamol.

This work aims to create an electrochemical sensor to detect paracetamol (PAR). The sensor is constructed by modifying an electrode with carbon paste and incorporating nanostructures of manganese cobaltite (MnCoO) onto reduced graphene oxide that is doped with nitrogen and boron (BN-rGO). MnCoO provides a stable structure and N, B-doped rGO enhances conductivity and provides additional active sites.

Efficacy and tolerability of subcutaneous repository corticotropin injection in refractory ocular inflammatory diseases.

Background: Repository corticotropin injection (RCI) has been suggested to exert immunomodulatory and anti-inflammatory effects in ocular inflammation. The index retrospective study aimed to evaluate the efficacy and tolerability of subcutaneous RCI in patients with active scleritis or uveitis.

Main Body: Medical records of patients who were diagnosed with different types of active scleritis or uveitis and received RCI for more than six months at a tertiary eye center were reviewed.