Publications by authors named "N Yamakawa"
Comprehensive microRNA analyses using vitreous humor of ocular sarcoidosis.
Graefes Arch Clin Exp Ophthalmol
September 2024
Purpose: MicroRNAs (miRNAs) are non-coding RNAs which have attracted attention as biomarkers in a variety of diseases. However, extensive unbiased analysis of miRNA in vitreous humor of sarcoidosis patients has not been reported. In the present study, we comprehensively analyzed the dysregulated miRNAs in ocular sarcoidosis to search for potential biomarkers.
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- The study focused on the effectiveness of first-line therapies—nivolumab, pembrolizumab, and cetuximab—for patients with unresectable recurrent or metastatic oral cancer, highlighting the gap in research specifically for this type of cancer as most data comes from head and neck cancer studies.
- It reviewed the outcomes of 155 patients, measuring overall survival (OS), progression-free survival (PFS), response rates, and side effects, and found no significant differences in survival rates among the three treatments.
- The conclusion emphasized the need for further research due to the small sample size and retrospective nature of the study, stating that there is not enough evidence to determine the most effective first-line therapy for unresect
Vital signs are crucial for assessing the condition of a patient and detecting early symptom deterioration. Noncontact sensor technology has been developed to take vital measurements with minimal burden. This study evaluated the accuracy of a mat-type noncontact sensor in measuring respiratory and pulse rates in patients with cardiovascular diseases compared to conventional methods.
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- * Out of 77 participants, a majority successfully performed daily self-monitoring, though younger patients and those with more severe HF symptoms were less consistent.
- * The findings suggest that self-telemonitoring is practical for older HF patients and may help in early detection of worsening conditions, potentially leading to better management and outcomes.
Background: The Union for International Cancer Control and American Joint Committee on Cancer tumor staging system is used globally for treatment planning. As it may be insufficient for tumor staging of lower gingival carcinomas, we proposed the mandibular canal tumor staging system. In this study, we aimed to compare the two systems for such tumor staging and to identify prognostic markers.
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