Publications by authors named "N Wulffraat"

Article Synopsis
  • A EULAR task force developed guidelines for educating young patients with juvenile-onset rheumatic and musculoskeletal diseases about managing physical activity and pain during their transition from pediatric to adult healthcare.
  • They formulated two overarching principles highlighting the need for personalized care and seven points to consider, emphasizing the importance of patient education for a smoother transition.
  • The guidelines are backed by moderate to weak levels of evidence and are intended to standardize care in Europe while encouraging further research and policy development in this area.
View Article and Find Full Text PDF

In children with juvenile idiopathic arthritis (JIA), the temporomandibular joint (TMJ) can be involved. To prevent TMJ damage due to inflammation, early recognition is important, for which contrast-enhanced magnetic resonance imaging (MRI) is the gold standard. In this study, the interobserver reliability and construct validity of the Juvenile Idiopathic Arthritis Magnetic Resonance Scoring System for Temporomandibular Joints (JAMRIS-TMJ) was assessed.

View Article and Find Full Text PDF

Background: In patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), momentary cortisol concentrations in blood, urine, and saliva are lower compared to healthy controls. Long-term cortisol concentration can be assessed through hair, but it is unclear whether these concentrations are also lower. Additionally, it is unknown if lower cortisol extends to other patients suffering from persistent fatigue and how hair cortisol concentration (HCC) relates to fatigue levels.

View Article and Find Full Text PDF

Background: Mandibular range of motion (MROM) variables are widely used to evaluate oral function.

Objective: The aim of this study was to establish the reliability of MROM variables in healthy children.

Methods: In this cross-sectional study, healthy children were examined 2 weeks apart.

View Article and Find Full Text PDF

Maternal autoimmune rheumatic diseases can influence the outcomes of children through several life stages. During pregnancy, maternal inflammation and autoantibodies can hinder fetal development and lead to growth restriction, preterm birth, and low birth weight; prematurity, especially at extreme gestational ages, can in turn impair future child health. Treatment with compatible immunomodulatory drugs and preventive medications aims to keep maternal disease under control and minimise the risk of adverse pregnancy outcomes.

View Article and Find Full Text PDF