BACKGROUND Priapism is a persistent penile erection that lasts longer than 4 hours. The most common causes of priapism are ischemia and the effects of drugs, including PDE-5 inhibitors, such as sildenafil and anticoagulants. Here, we describe the presentation and management of a 50-year-old man with priapism following coronary artery angiography for the investigation of ischemic heart disease (IHD).
View Article and Find Full Text PDFObjective: To evaluate the effect of Zhigancao decoction on reversal of right atrial myocardial fibrosis after rapid atrial pacing (RAP)-induced atrial fibrillation (AF).
Methods: New Zealand white rabbits were randomly divided into four groups: sham operation group (Group A: implanted electrodes, no RAP), pacing group (Group B: RAP-induced AF), Zhigancao soup water decoction Yin group (Group C: RAP-induced AF followed by Zhigancao soup Yin prescription twice a day for 30 days), and Zhigancao soup group (Group D: RAP-induced AF followed by Zhigancao water decoction twice a day for 30 days). The atrial myocardium was then examined for myocardial fibrosis by Masson staining, and protein expression of matrix metalloproteinase-9 (MMP-9) was immunohistochemically assessed.
Background: Chronic heart failure (HF) is the main complication of various organic heart diseases. An imbalance of the autonomic nervous system has close associations with arrhythmia, ventricular remodeling, and sudden death upon HF. This study investigated whether unilateral vagus nerve stimulation could increase vagal activity, improve autonomic nerve distribution, and cardiac function in a HF model.
View Article and Find Full Text PDFBackground: This study sought to examine the effect of the cardiac autonomic nerve plexus, which originates from the vagus nerve trunk, on atrial vulnerability.
Methods: Dogs in group I (n = 6) underwent ganglionated plexi (GP) sequential ablation following six hours of left atrial appendage rapid atrial pacing (RAP). The monophasic action potential duration at 90% of repolarization (APD90), effective refractory period (ERP), and the atrial fibrillation inducing rate of bilateral atria and pulmonary veins were recorded at baseline, l h, 3 h and 6 h after pacing, as well as after sequential ablation (RAGP + RIGP ablation, LSGP + RIGP ablation).