D-Dimer Elevation at Time of Admission is Associated with Need for Ventilator Support among Pediatric Patients with COVID-19 Infection.

Background: This study aims to determine if coagulation abnormalities at presentation are associated with clinical severity of pediatric COVID-19 infection.

Methods: We retrospectively reviewed admission coagulation studies (D-dimer, prothrombin time (PT), partial thromboplastin time with hepzyme, fibrinogen, and platelet count) with disease severity defined by need for ICU admission, ventilator support, and length of stay (LOS).

Results: There were 110 pediatric patients (0.

Reconstruction of the mandibular condyle due to degenerative disease.

Degenerative joint disease (DJD), also known as osteoarthritis is the most common form of arthritis and can affect the temporomandibular joint (TMJ). TMJ DJD is characterized by degradation of the articular cartilage and synovial tissues resulting in characteristic morphologic changes in the underlying bone. DJD can occur at any age, but it is more common in older age groups.

PRSS50 is a testis protease responsible for proper sperm tail formation and function.

Multiple morphological abnormalities of the sperm flagella (MMAF) are a major cause of asthenoteratozoospermia. We have identified protease serine 50 (PRSS50) as having a crucial role in sperm development, because Prss50-null mice presented with impaired fertility and sperm tail abnormalities. PRSS50 could also be involved in centrosome function because these mice showed a threefold increase in acephalic sperm (head-tail junction defect), sperm with multiple heads (spermatid division defect) and sperm with multiple tails, including novel two conjoined sperm (complete or partial parts of several flagellum on the same plasma membrane).

Can extraoral suction units minimize droplet spatter during a simulated dental procedure?

Background: Aerosol and droplet production is inherent to dentistry. Potential for COVID-19 spread through aerosols and droplets characterizes dentistry as having a high risk of experiencing viral transmission, with necessity for aerosol and droplet mitigation.

Methods: Simulations of restorative treatment were completed on a dental manikin with a high-speed handpiece and high-volume evacuation suction.

E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling.

Cryptorchidism is the most common urologic birth defect in men and is a predisposing factor of male infertility and testicular cancer, yet the etiology remains largely unknown. microdeletions and microduplications contribute to cryptorchidism, infertility and testicular tumors. Although deletion or overexpression in mice causes spermatogenic failure, the mechanism by which influences testicular function is unknown.